frozen section

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frozen section

 
a specimen of tissue that has been quick-frozen, cut by microtome, and stained immediately for rapid diagnosis of possible malignant lesions. A specimen processed in this manner is not satisfactory for detailed study of the cells, but it is valuable because it is quick and gives the surgeon immediate information regarding the malignancy of a piece of tissue.

fro·zen sec·tion

a thin slice of tissue cut from a frozen specimen, often used for rapid microscopic diagnosis.

frozen section

Cryostat section, 'frozen,' quick section Surgical pathology A rapid diagnostic procedure performed on tissue obtained intra-operatively, which is frozen in a synthetic material–eg, OCT–Miles Labs, sectioned with a cryostat, stained with H&E and viewed with a LM, allowing a rapid diagnosis of a pathologic tissue; a FS provides a surgeon with information necessary to guide therapy, and to determine the extent of further surgery at the time of surgical procedure
Frozen section–indications
1. Differentiate between benign and malignant
.
2. Determine type of malignancy–eg, lymphoma v. carcinoma
.
3. Evaluate tissue margins for involvement by malignancy, eg basal cell carcinomas
.
4. Determine adequacy of tissue for further studies after the Pt is closed
.
5. Determine type of tissue, eg differentiate lymphoid tissue from parathyroid gland
.

fro·zen sec·tion

(frō'zĕn sek'shŭn)
A thin slice of tissue cut from a frozen specimen, often used for rapid microscopic diagnosis.

frozen section

A method of obtaining a while-you-wait opinion on a BIOPSY specimen. The tissue block is frozen solid with dry ice so that thin slices can be cut, mounted on slides, stained and immediately examined under the microscope. Frozen sections are often called for in the course of an operation for suspected cancer. The result may radically alter the surgical procedure performed.