fipronil
(redirected from Frontline (product))fipronil
(fip-rō'nil),A phenylpyrazole parasiticide agent that is available as pourable topical solution and spray for flea and tick infestation in dogs and cats; mechanism of action is to disrupt chloride passage through gamma amino butyric acid-mediated channels in nerve cell membranes, resulting in terminal neurologic malfunction. Commercial solutions are flammable.