Wegener, Friedrich

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Friedrich, German pathologist, 1907-1990.
Wegener granulomatosis - characterized by necrotizing granulomas and ulceration of the upper respiratory tract, with purulent rhinorrhea, nasal obstruction, and sometimes with otorrhea, hemoptysis, pulmonary infiltration and cavitation, and fever.
Medical Eponyms © Farlex 2012
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Granulomatoz polianjit (Wegener granulomatozu) ilk kez 1936 yilinda Alman patolog Friedrich Wegener tarafindan "rinojenik granulomatoz" adiyla tanimlanan sistemik, nekrotizan ve granulomatoz bir vaskulittir [1].
Granulomatosis with polyangiitis (GPA), formerly known as Wegener granulomatosis, (1) is an autoimmune vasculitis that affects multiple organ systems and was first described in 1936 by Friedrich Wegener. (2) The 1990 American College of Rheumatology (3) criteria for diagnosis of GPA include (1) nasal or oral inflammation, (2) respiratory radiographic abnormalities consistent with respiratory tissue destruction (eg, nodules, infiltrates, and cavities), (3) microhematuria or red blood cell casts on urinary sediment analysis, and (4) granulomatous inflammation on biopsy for pathology.
Wegener's granulomatosis (WG) is an immunologically mediated uncommon multi-system disorder, first described by Friedrich Wegener in 1936.
Detailed description of the disease was given by Friedrich Wegener in 1936 and 19393,4.
The condition was not formally described until 1936 when a landmark presentation was published in the Proceedings of the German Pathological Society by Dr Friedrich Wegener describing 3 patients with a systemic illness affecting the upper and lower respiratory tract and renal system [4].
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