Freund's adjuvant


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.
Related to Freund's adjuvant: Freund's incomplete adjuvant

Freund's adjuvant

(froindz)
n.
A substance consisting of killed microorganisms, such as mycobacteria, in an oil and water emulsion that is administered to induce and enhance the formation of antibodies.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

Freund's adjuvant

An emulsion of killed bacteria in oil that induces antibody formation. (Jules Thomas Freund, 1890–1960, Hungarian-born American bacteriologist).
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive ?
(A) Total leukocytes; (B) Differential leukocyte count--mononuclear (Mono) and polymorphonuclear (PMN) in groups of animals: control (C); control treated by autohemotransfusion (CT); Complete Freund's Adjuvant induced arthritis 0.5% w/v (AIA); Complete Freund's Adjuvant induced arthritis 0.5%w/v treated with autohemotransfusion (AIAT); Complete Freund's Adjuvant induced arthritis 0.1% w/v (AS) and Complete Freund's Adjuvant induced arthritis 0.1% w/v treated with autohemotransfusion (AST).
Dysregulated miRs found in trigeminal ganglions from complete Freund's adjuvant (CFA)-injected mice assessed by RT-qPCR at each time-point (n=6).
However, this study showed that the desired antibody response could be obtained using the Montanide[TM] ISA 61 VG water-in-oil adjuvant as an alternative to Freund's adjuvant without conjugating any carrier protein such as BSA to the KDN molecule.
(1996) where they used Montanide ISA 50 oil adjuvant was shown to be similarly effective to the Freund's adjuvant preparation on laboratory challenge of immunised goats and sheep.
Cytokine analysis showed that PapG.AcmA, as a vaccine, in combination with both alum and freund's adjuvants could strongly induce in immune-deficient IFN-g secretion and polarize the Th1 pattern.
The first group was used as control while the second group has received oral dosage of STGs and Freund's adjuvant. The rats were housed in a cage, according to NIH guidelines with free access to distilled water and food.
tuberculosis) suspended in liquid paraffin (Freund's adjuvant) in rats induced arthritis by producing chronic inflammation of the articulations in genetically predisposed animals [20].
(India), and complete Freund's adjuvant was obtained from Sigma-Aldrich (USA).
Incomplete Freund's Adjuvant (IFA) was used instead of the Freund's complete
The aim of this study therefore was to investigate the wound healing effect of Hypericum perforatum flowers sojaoil extract (Rotoel[R]) in a model of experimental trauma in Freund's adjuvant arthritic Wistar rats.
High antibody titers ranging from 1:[10.sup.4] in the first week to 1:[10.sup.6] in the fourth week were detected in immunized rabbits, whereas serum and pre-immune serum of control rabbits with only Freund's adjuvant showed a negligible amount of antibodies, i.e.