Fraser syndrome

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Fra·ser syn·drome

(frā'zĕr), [MIM*219000]

an association of cryptophthalmos with multiple anomalies, including middle and outer ear malformations, cleft palate, laryngeal deformity, displacement of umbilicus and nipples, digital malformations, separation of symphysis pubis, maldevelopment of kidneys, and masculinization of genitalia in females; autosomal recessive inheritance.

Synonym(s): cryptophthalmos syndrome

Fra·ser syn·drome

(frā'zĕr sin'drōm)

An association of cryptophthalmus with multiple anomalies, including middle and outer ear malformations, cleft palate, laryngeal deformity, displacement of umbilicus and nipples, digital malformations, separation of symphysis pubis, maldevelopment of kidneys, and masculinization of genitalia in females; autosomal recessive inheritance.

Fraser,

George R., English geneticist, 1932–.

Fraser syndrome - an association of cryptophthalmus with multiple anomalies. Synonym(s): cryptophthalmus syndrome

Fraser syndrome - see under Melnick, M

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References in periodicals archive ?

INTRODUCTION: Fraser Syndrome or Meyer-Schwickerath's Syndrome or Fraser-Francois Syndrome is an autosomal recessive congenital disorder first described by Canadian geneticist C.R.

Epidemiology: The incidence of Fraser Syndrome is 0.043 per 10, 000 live born infants and 1.1 in 10,000 still births making it a rare syndrome.

Fraser Syndrome: A clinical study of 59 cases and evaluation of diagnostic criteria.

Fraser syndrome in a female baby aged 2months--a case report

In his new autobiography, Hard Knocks And Soft Spots, Paddy has also revealed how he and Roseanne have lost four babies - three girls and a boy - to the rare genetic disease Fraser syndrome.

MY AGONY OVER CRASH TRAGEDY

After having five healthy children, their next four died from a genetic disorder called Fraser syndrome.

From being shot in the Speaker's wife... my honesty always gets me in trouble

Other disorders to be considered in a case of congenital eyelid coloboma include Franceschetti Syndrome, Oculoauricular dysplasia (Goldenhar syndrome)3, Amniotic band syndrome, Cryptophthalmos (Fraser syndrome)4,5 and Manitoba Oculotrichoanal (MOTA) syndrome6.

REPAIR OF BILATERAL CONGENITAL UPPER EYELID COLOBOMA- A CASE REPORT

This case reports only the second case of Fraser Syndrome (FS) in the dental literature, and the first with hypodontia and shortened roots.

Fraser syndrome is a rare syndrome which is more frequent in consanguineous parents.

The present case is the first report to describe hypodontia and shortened roots in Fraser syndrome.

Case report: hypodontia and short roots in a child with Fraser syndrome

ASSOCIATED ANOMALIES: The most frequently associated syndrome observed with CHAOS is Fraser syndrome which is characterized by malformations of the larynx, cryptophthalmos, syndactyly, genitourinary tract, craniofacial dysmorphism, orofacial clefting, mental retardation, and musculoskeletal anomalies.

Laryngeal atresia presenting as fetal ascites, olygohydramnios and lung appearance mimicking cystic adenomatoid malformation in a 25-week-old fetus with Fraser syndrome. Prenat Diagn 1999; 19: 856-8.

Congenital high airway obstruction (CHAOS) syndrome: a rare case presentation

They died when they were just babies, after Paddy and Roseanne discovered they suffered from a condition called Fraser syndrome, a rare genetic condition which is almost always fatal.