fractional shortening


Also found in: Acronyms.

fractional shortening

The reduction of the length of the end-diastolic diameter that occurs by the end of systole. Like the ejection fraction, this is a measure of the heart's muscular contractility. If the diameter fails to shorten by at least 28%, the efficiency of the heart in ejecting blood is impaired.
References in periodicals archive ?
Phillips & Harkin (2003) diagnosed hypothyroidism and cardiac failure in two dogs, whose echocardiographic findings were similar to those documented in subjects diagnosed with dilated cardiomyopathy, including diminished fractional shortening and augmented left ventricular internal diameters in systole and diastole.
As shown in Figures 3(c) and 3(d), exposure to sevoflurane did not affect systolic function, as represented by fractional shortening and fractional area change in CD-fed rats.
Left ventricular systolic function was taken as LVEF and fractional shortening (FS).
The echo variables tested were left atrial size, left ventricular wall thickness, and fractional shortening. But even using all three of these variables together led to only a slight improvement in predictive accuracy, and they were judged to not be worth including in the risk formula, Dr.
Risk factors for stroke include being aged 75 years or older and having hypertension, impaired left ventricutar systolic function (an ejection fraction of 35% or less or a fractional shortening of less than 25%), diabetes, prior thromboembolism, or rheumatic mitral stenosis.
Left ventricular fractional shortening also was similar at birth in HIV-1-infected infants and the internal controls.
LVSD was defined as fractional shortening less than 25% by echocardiography, or if systolic function was significantly impaired" when quantitative measures were unobtainable.
Left ventricular fractional shortening was calculated by the following formula: [left ventricular-end diastolic diameter (LVDD)--left ventricular-end systolic diameter x 100]/LVDD.
Additionally, left ventricular percentage fractional shortening was calculated as a synthetic index of left ventricular systolic function [18].
Administration of MYK-491 resulted in approximately 10% relative increases from baseline in cardiac contractility across multiple echocardiographic measures, including stroke volume, left ventricular ejection fraction and fractional shortening. In increasing the heart's contractility, MYK-491 did not appear to meaningfully change duration of the contraction or the heart's ability to relax and fill with oxygenated blood.
On baseline or diagnostic echo, left ventricular ejection fraction and fractional shortening were statistically significant predictors of clinical outcome (p<0.05 each).
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