Table 1: Antihypertensive agents for the treatment of hypertension in patients receiving hemodialysis Class and Agent Dose in Dialysis Common Adverse Effects ACE Inhibitors: 10-40 mg PO q12-24 Hours Hyperkalemia, dizziness, Fosinopril
5-10 mg PO Once Daily headache, taste Ramipril Dose after hemodialysis disturbance, dry cough, hypotension, rash ARBs: 16-32 mg PO Once Daily Hyperkalemia, dizziness, Candesartan 20-80 mg PO Once Daily headache, hypotension Telmisartan No dose adjustment required in hemodialysis Beta-blockers: 6.
08 mg/kg/d up renal artery ([dagger]) to 5 mg stenosis (qd-bid) Fosinopril
Some commonly prescribe drugs in this class include captopril (Capoten), enalapril (Vasotec), lisinopril (Prinivel, Zestril), benazepril (Lotensin), fosinopril
(Monopril), moexipril (Univasc), perindopril (Aceon), ramipril (Altace) and trandolapril (Mavik).
tablets (Monopril) 10 mg, 20 mg and 40 mg in 90-count bottles
In contrast, throughout the survey area, only the originator brand of fosinopril
and two famotidine products were found, and each of the two medicines was only available at a single outlet (representing 1% of all outlets).
These drugs include captropril (Capoten), fosinopril
(Monopril), lisinopril (Prinivil or Zestri), perdopril (Aceon), ramipril (Altace), and trandolapril (Mavik).
Some ACE inhibitors are known as "centrally-acting" because they can cross the blood-brain barrier- a specialized system of tiny blood vessels that protects the brain from harmful substances in the blood stream-that include captropril, fosinopril
, perindopril, ramipril and trandolapril.
seems to be the only ACE inhibitor to reduce Lp(a) concentrations in non-proteinuric patients as well, probably by increasing apo(a) fragmentation and excretion into the urine (Kostner K et al.
500 mg Duration of 3 weeks 5 months therapy Co-medication Labetolol, fosinopril
, Valaciclovir, verapamil, metformin, pseudo-ephedrine, and insulin, aspirin, and ibuprofen aminosalicylic acid Co-morbidity Polymyositis, diabetes n.
Other medications commonly used to treat hypertension include beta blockers such as atenolol (Tenormin), calcium channel blockers such as amlodipine (Norvasc), angiotensin II receptor antagonists such as losartan (Cozaar), and angiotensin-converting enzyme (ACE) inhibitors such as fosinopril
The angiotensin-converting enzyme inhibitor, fosinopril
, and the angiotensin II receptor antagonist, losartan, inhibit LDL oxidation and attenuate atherosclerosis independent of lowering blood pressure in apolipoprotein E deficient mice.