The M2s are Symmetrel (amantadine) and
Flumadine, both of which are dosed at 100 mg twice a day.
$4.04 (
Flumadine) (tablet) amantadine 100 mg b.i.d.
Although prophylaxis with amantadine (Symmetrel) and rimantadine (
Flumadine) provides a 60%-70% protection from influenza A illness, these drugs have a limited use in infants.
In cases where you're considering use of an antiviral in a season predominated by influenza A (as was the case this year), don't forget amantadine (Symmetrel) and rimantadine (
Flumadine), which are cheaper than oseltamivir.
Genetic sequencing and antiviral susceptibility testing of five human H5N1 isolates indicate the viruses have resistance to amantadine (Symmetrel) and rimantadine (
Flumadine).
Genetic sequencing and antiviral susceptibility testing of five human H5N1 isolates indicate that the viruses have resistance to amantadine (Symmetrel) and rimantadine (
Flumadine).
Amantadine (Symmetrel) and rimantadine (
Flumadine) have been approved for type A influenza in children older than 1 year, said Dr.
(
Flumadine) (tablet) Listed dosage is for treatment and prophylaxis.
Flumadine (rimantadine) is not indicated at all for treatment of influenza A virus in children, only for prophylaxis in children 1 year and older, according to a spokeswoman from Forest Pharmaceutical Inc.
Remember that Tamiflu (oseltamivir) is only approved for children aged 5 years and older, while Relenza (zanamivir),
Flumadine (rimantadine), and Symmetrel (amantadine) are approved for children older than 1 year.
The tricyclic amines, amantadine (Symmetrel) and rimantadine (
Flumadine), can cause central nervous system effects such as dizziness, altered mental status, and hallucinations.
Remember that we also have two modestly effective, easy to use antivirals with minimal adverse reactions available--osehamivir (Tamiflu) and rimantadine (
Flumadine).