FluMist


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influenza vaccine (nasal)

(in-floo-en-za vak-seen) ,

FluMist

(trade name)

Classification

Therapeutic: vaccines immunizing agents
Pregnancy Category: C

Indications

Active live immunization for prevention of disease caused by Influenza A and B.

Action

Active immunization with live virus produces antibodies against Influenza.

Therapeutic effects

Decreased influenzal illness, with fewer days lost from school or work.

Pharmacokinetics

Absorption: Virus replicates in nasopharynx causing production of antibodies.
Distribution: Unknown.
Metabolism and Excretion: Unknown.
Half-life: Unknown.

Time/action profile

ROUTEONSETPEAKDURATION
Intranasalunknownunknownunknown

Contraindications/Precautions

Contraindicated in: Obstetric: Pregnancy; Hypersensitivity to FluMist, eggs, or egg products; History of asthma or reactive airways disease; Other live vaccine within 1 mo or inactivated vaccine within 2 weeks; Concurrent immunosuppressive therapy or disease causing immunosuppression or immunocompromise; Antiviral agents (not for 48 hr prior or 2 wk after); Pediatric: Children or adolescents (5–17 yr) receiving aspirin, aspirin-containing or salicylate therapy (risk of Reye syndrome); Chronic illness including cardiac/pulmonary disease, metabolic disease, renal impairment or hemoglobinopathy; History of Guillain-Barré.
Use Cautiously in: Obstetric / Pediatric: Lactation, children <2 yr, patients >50 yr (safety not established).

Adverse Reactions/Side Effects

Central nervous system

  • headache

Ear, Eye, Nose, Throat

  • rhinitis
  • nasal congestion

Miscellaneous

  • fever

Interactions

Drug-Drug interaction

Concurrent use of aspirin or salicylates in children/adolescents may ↑ risk of Reye syndrome.Concurrent antiviral therapy (may affect desired immune response to FluMist).

Route/Dosage

Intranasal (Adults and Children 9–49 yr) One dose (0.5 mL)/season.
Intranasal (Children 2–8 yr) Previously immunized with FluMist—one dose (0.2 mL)/season; not previously immunized with FluMist—two doses (0.2 mL each)/30 days apart for initial season.

Availability

Pre-filled single-use intranasal sprayer: 0.5 mL/sprayer, 0.2 mL/sprayer

Nursing implications

Nursing assessment

  • Assess patient for history of asthma or reactive airway disease. Patients with positive history should not receive FluMist.
  • Lab Test Considerations: Monitor patient for signs of allergic reaction (rash, pruritus, laryngeal edema, wheezing) following administration. Keep epinephrine, an antihistamine, and resuscitation equipment close by in case of an anaphylactic reaction.

Potential Nursing Diagnoses

Deficient knowledge, related to medication regimen (Patient/Family Teaching)

Implementation

  • Do not administer rimantidine or other antiviral agents within 48 hrs before or 2 wks after administration intranasal influenza virus vaccine (FluMist).
  • Store solution in refrigerator until just before use; do not freeze. Solution should be colorless to pale yellow and clear to slightly cloudy.
    • Do not administer FluMist concurrently with other vaccines, or in patients who have received a live virus vaccine within 1 mo or an inactivated vaccine within 2 wks of vaccination.
  • Intranasal: With the patient in an upright position, approximately 0.25 mL (half the dose of a single FluMist sprayer) is administered into each nostril. Insert the tip of the sprayer just inside the nostril and depress the plunger to spray. Remove the dose divider clip and administer the second half of the dose into the other nostril. Dispose of sprayer in routine for biohazard disposal.

Patient/Family Teaching

  • Explain to patient and parent the purpose of the vaccination.
  • Advise patient to avoid contact with patients who are immunocompromised for at least 21 days.

Evaluation/Desired Outcomes

  • Prevention of influenza resulting in fewer lost days from work and school.

FluMist

Influenza vaccine, live, intranasal.
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References in periodicals archive ?
"Wyeth's exit from the collaboration for FluMist returns all rights to the vaccine's franchise to MedImmune; we look forward to transitioning activities from Wyeth and implementing our development and commercialization plan."
This policy was the ACIP's original intent, but the ambiguous wording in last fall's LAIV statement caused confusion, with many providers interpreting the wording to mean that FluMist was "contraindicated" or "not recommended" for health care workers in general, Dr.
State and local governments will now be able to purchase Flumist at a discounted rate, according to the Department of Health and Human Services.
However, in research my group has conducted for Medimmune, we have used Flumist in selected high-risk patients after discussing it with the parents and obtaining informed consent.
The CDC continues to recommend that the quadrivalent live attenuated influenza vaccine FluMist not be used by anyone for the 2017-2018 season, a decision that was made after evidence showed poor effectiveness against influenza A(HlNl)pdm09 viruses in the 2013-2014 and 2015-2016 seasons.
3,300 vaccinations, provide the vaccine, syringes, biohazard containers, needles and other supplies necessary to administer the immunization, provide flumist as an alternative for employees who are medically qualified and want this alternative, as available, see attached file.
"Changes are related to concerns regarding low effectiveness of [LAIV] (FluMist, Medlmmune) against influenza A(H1N1)pdm09 in the United States during the 2013-2014 and 2015-2016 influenza seasons," wrote the authors of the report, published in Annals of Internal Medicine and led by David K.
For this year, the 2016/2017 flu season, the Advisory Committee on Immunization Practices (ACIP) has recommended that no one is to use the FluMist nasal flu vaccine.
Paediatricians across the Atlantic say they won't recommend the vaccine, known there as FluMist, this winter season.
Christie, a Republican who recently launched an organization that allows him to raise money for a possible 2016 presidential campaign, was asked about the outbreak after touring a facility operated by MedImmune, which manufacturers the flu vaccine FluMist. Christie is on a three-day UK trip.
The vaccine is also available in a FluMist nasal spray.
Of course, if you really have a thing about needles, you could inhale your flu vaccine in the form of the nasal spray called FluMist. But it's approved only for people 2 to 49 years old, so if you're not in that age range, you're out of luck.