Darifenacin (Enablex), fesoterodine (Toviaz), flavoxate
(Urispas), oxybutynin (Ditropan), solifenacin (Vesicare), tolterodine (Detrai), and trospium (Sanctura).
Incontinence Drugs: Darifenacin, Flavoxate
, Oxybutynin, Tolterodine,
y Haleem A.: "Plastic membrane electrodes for the determination of flavoxate
hydrochloride and cyclopentolate hydrochloride".
In the first quarter of 2000, the vast majority of users were treated with oxybutynin (68.6%; 10.4 users/1,000 beneficiaries) with the only other treatments being flavoxate
(17.7%; 2.7 users/1,000 beneficiaries) and tolterodine (13.7%; 2.1 users/1,000 beneficiaries).
There are no human pregnancy data for six of these agents and very limited data for flavoxate
From the first real FDA-approved OAB drug (flavoxate
) in 1970, to oxybutynin in 1975, current OAB medications have fewer side effects and are far more effective (Hesch, 2007).
The antispasmodic medication flavoxate
(Urispas[R]) often was ordered for women at the project site.
(a synthetic flavone derivative) inhibits L-type [Ca.sup.2+] channels in human detrusor (Tomoda et al.
Seeing that the patient had asthma exacerbation at the same time, she was administered with montelukast sodium (10mg/d) and flavoxate
For inhibition of L-Type Calcium channel, NMDA receptor and CaM kinase, cells were preincubated with, adding 1.8 mM ketamine and 1[micro]M MK801, 15 min (treatment 1), 100 [micro]M nifedipine and 100 [micro]M flavoxate
hydrochloride, 30 min (treatment 2) and 10 [micro]M trifluoperazine, 30 min (treatment 3).
There are seven anticholinergics that are used as antispasmodics for the treatment of overactive bladder: darifenacin (Enablex) [C], fesoterodine (Toviaz) [C], flavoxate
(Urispas) [B], oxybutynin (Ditropan) [B], solifenacin (Vesicare) [C], tolterodine (Detrol) [C], and trospium (Sanctura) [C].