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a platinum coordination compound whose main mode of action resembles that of alkylating agents with production of cross links between the two strands of DNA in the double helix so that DNA cannot be replicated and the cells cannot divide. It is used as an antineoplastic agent in the treatment of metastatic tumors of the testis, ovary, bladder, and head and neck. It can cause serious damage to the kidney, eighth cranial nerve, gastrointestinal tract, and bone marrow, can upset metabolic processes, and can produce hypocalcemia and hypomagnesemia. Called also DDP or cis-DDP.


Notation for the gene for DFN1.



cis- DDP



Mohr-Tranebjaerg syndrome

An autosomal recessive neurodegenerative syndrome (OMIM:304700) characterised by postlingual progressive sensorineural deafness as the first presenting symptom in early childhood, followed by progressive dystonia, spasticity, dysphagia, mental deterioration and cortical blindness.

Molecular pathology
Defects of TIMM8A, which encodes a translocase, cause Mohr-Tranebjaerg syndrome.


diaminedichloroplatinum, a heavy metal complex; used as an antineoplastic agent. See also cisplatin.

Patient discussion about DDP

Q. Is pervasive developmental disorder (PDD) or autism is fatal……what exactly it is……?

A. Autism is not fatal in its symptom and progression but it can become fatal as it does impair normal physiological function it CAN BE a fatal condition. It’s a group of illness which involves delays in the development of basic skills. It happens to children below age 3. It affects the child`s ability to communicate and interact. Autism affected children are also found to be mentally retarded.

Q. I was at my colleague's home and one of his kids kept talking to herself he said that she has PDD. i later asked my wife about it and she said she thinks it's a type of autism. but other than talking to herself the girl seemed perfectly normal. so is PDD a light version of autism?

A. I didn't really understand everything in this web page, but I think I get the big picture. Thanx

Q. What resources are available in Seattle, Washington to help with an autistic child?

A. i miss Seattle... here is a link to "Autism Spectrum Treatment and Research (ASTAR) Center". a well know establishment:


More discussions about DDP
References in periodicals archive ?
For more than two years, I concealed my identity for scientific purposes, but now that my experiment is essentially complete, corporate America having fulfilled (albeit a year later than expected) its final phase, I finally feel compelled to offer a report: on the flash mob, its life and times, and its consummation this summer in the clutches of the Ford Motor Company.
In addition, out of simple "pokatushki" in combat form and with flags, flash mob has grown into a really big holiday, where, on the initiative of firemen and rescuers themselves, about ten different interactive platforms are organized, on which contests, quizzes and relay races are held.
The interactive flash mob supports the ambulance corporation's efforts to enable and empower society with the necessary experience to deal with medical emergencies.
The Organ Donation Wales flash mob at Cardiff Central
Activists and students of the Bishkek Humanities University (BHU) will hold Save the Light flash mob, the Ministry of Energy press service reported today.
Students from Glyndwr University put on a flash mob performance of some of the show's most popular songs at Eagles Meadow shopping centre in Wrexham.
IT was a quiet night of festive shopping - until dozens of students broke out into a flash mob to raise awareness of a cancer charity.
WORCESTER -- City officials attended a ceremonial flash mob held Wednesday afternoon behind City Hall to raise awareness for people with blindness and other disabilities.
Another flash mob is to take place in schools again on Friday.
s flash mob, danced to Nina Simone's "I Wish I Knew How It Would Feel to Be Free," and an arrangement of H.
Visitors to the event enjoyed a fast-paced fashion show, film screenings and music performances, which included a zombie flash mob performed by the college's BTEC performing arts students.
A FLASH mob with a difference made a song and dance in Coventry city centre at the weekend - for dementia awareness.