fixative

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fixative

 [fik´sah-tiv]
an agent used in preserving a histologic or pathologic specimen so as to maintain the normal structure of its constituent elements.

fix·a·tive

(fik'să-tiv),
1. Serving to fix, bind, or make firm or stable.
See also: fluid, solution.
2. A substance used for the preservation of gross and histologic specimens of tissue, or individual cells, usually by denaturing and precipitating or cross-linking the protein constituents.
See also: fluid, solution.

fixative

(fĭk′sə-tĭv)
n.
Something that fixes, protects, or preserves, especially:
a. A liquid preservative applied to artwork, such as watercolor paintings or charcoal drawings.
b. A solution used to preserve and harden fresh tissue for microscopic examination.
c. A liquid mixed with perfume to prevent rapid evaporation.

fix′a·tive adj.

fix·a·tive

(fik'să-tiv)
1. Serving to fix, bind, or make firm or stable.
2. A substance used for the preservation of gross and histologic specimens of tissue, or individual cells, usually by denaturing and precipitating or cross-linking the protein constituents.
See also: fluid, solution

fix·a·tive

(fik'să-tiv)
1. Serving to fix, bind, or make firm or stable.
2. A substance used for the preservation of gross and histologic specimens.
References in periodicals archive ?
The standard fixative for tissue destined for light microscopy analyses is 4% formaldehyde, which is used interchangeably with 10% neutral buffered formalin, 10% buffered formalin phosphate (Fisher Chemical, https://www.
Fixation in nonformalin fixatives such as Bouin or Hollande and prolonged (more than 10 years) storage of prostate biopsy paraffin blocks are associated with diminished staining.
The cell block is prepared from the liquid fixative deposit by adding equal amount of cell block fixative (10% formalin and 95% alcohol), got during MLBC procedure.
Systematic comparison of tissue fixation with alternative fixatives to conventional tissue fixation with buffered formalin in a xenograft-based model.
Prior to the introduction of Advantage 4910 hair fixative polymer, only one polymer manufacturer supplied octylacrylamide/acrylates/butylaminoethyl methacrylate copolymer.
The fixative then captures and fixes radioactive materials, metals and other contamination in place.
Then we used the obtained compound as a new fixative in the stabilization of herbal tissues for SEM imaging," Dr.
The firm will now transfer to zinc-free versions of the fixatives.
Because RNAlater is readily used for field sample transportation, laboratory assistants could falsely interpret RNAlater as a disinfectant fixative. Therefore, RNAlater-treated specimens should be marked as potentially infective materials.
The problem with pigment fixatives is that sometimes the color might make the product look fresh, but the meat or seafood in question might actually be spoiled despite its appetizing appearance.
Fixatives developed in the past were designed for use only on a small scale and in controlled environments, such as inside the containment building for a nuclear-power reactor, notes physicist Christina A.
Specially designed test sample holders are said to eliminate the need for grease or other lubricant fixatives. The oxygen transmission rate (OTR) is provided directly on the screen in ml/[m.sup.2].