Fish Mouth Vertebrae

A descriptive term for biconcave fishmouth-like vertebrae, caused by infarction and central bone collapse due to thrombosis of the vertebral arteries, a finding typical of sickle cell anaemia, which often occurs before the second decade of life; peripheral perforating metaphyseal arteries are relatively spared, explaining lesser involvement of the anterior and posterior faces of the vertebra
DiffDx Fishmouth vertebra may also be seen in hereditary spherocytosis, homocystinuria, Gaucher’s disease, osteoporosis, osteopaenia, renal osteodystrophy or hyperparathyroidism, osteomalacia, thalassemia major, blood dyscrasia
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