fibroblast growth factor


Also found in: Dictionary, Thesaurus, Legal, Financial, Acronyms, Encyclopedia, Wikipedia.
Related to fibroblast growth factor: Epidermal growth factor, Basic fibroblast growth factor

fibroblast growth factor

Any of a group of polypeptides that stimulate the growth of tissues rich in fibroblasts, including blood vessels, connective tissues, and skin. Overactivity of these factors has been associated with neoplasia.
See also: factor
References in periodicals archive ?
Expression of fibroblast growth factor receptor 1 (FGFR1) measured by RT-qPCR (A and B) and immunohistochemical (IHC) staining (C and D; magnification 100 x , 50[micro]pm) in 74 pairs of tumor (T) tissues and adjacent non-tumorous (N) tissues from gastric cancer patients.
Chow et al., "Role of circulating fibroblast growth factor 21 measurement in primary prevention of coronary heart disease among chinese patients with type 2 diabetes mellitus," Journal of the American Heart Association, vol.
Rebling et al., "The phosphatonin fibroblast growth factor 23 links calciumphosphate metabolism with left-ventricular dysfunction and atrial fibrillation," European Heart Journal, vol.
Grose, "Fibroblast growth factor signalling: from development to cancer," Nature Reviews Cancer, vol.
Marycz, "Basic fibroblast growth factor inhibits apoptosis and promotes proliferation of adipose-derived mesenchymal stromal cells isolated from patients with type 2 diabetes by reducing cellular oxidative stress," Oxidative Medicine and Cellular Longevity, vol.
Abbreviations FGF21: Fibroblast growth factor 21 MyoG: Myogenin CDKs: Cyclin-dependent kinases MAPK: Mitogen-activated protein kinase PI3K: Phosphoinositide 3-kinase UCP1: Uncoupling protein 1 PGC1[alpha]: Peroxisome proliferator-activated receptor gamma coactivator 1-alpha.
It included 7-d-old male rats that were randomised into four groups: fibroblast growth factor 2-20, fibroblast growth factor 2-40, control and sham.
We selected six fibroblast growth factor genes and two fibroblast growth factor receptor genes from which we designed eight primer pairs for qPCR validation (Supplementary Table S1).
Fibroblast growth factor 21 (FGF21) is a typical member of the fibroblast growth factor family.
Because the VEGF was being neutralised by Avastin, the cancer cells instead produced more FGF (fibroblast growth factor), another protein involved in the creation of blood vessels.
--Canada patent 2,459,957--This patent contains claims related to the feeder-free culture of pluripotent stem cells wherein the stem cells are grown on an extracellular matrix and stimulated to grow with a fibroblast growth factor. In addition, the patent contains additional claims such as to genetically-modified pluripotent stem cells grown on such feeder-free conditions.