fexofenadine(redirected from Fexofenedine)
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fexofenadine/fex·o·fen·a·dine/ (fek″so-fen´ah-dēn) an antihistamine (H1-receptor antagonist) used as the hydrochloride salt in the treatment of hay fever and chronic idiopathic urticaria.
A nonsedating antihistamine, C32H39NO4, used in its chloride form to treat allergic rhinitis and allergic skin disorders.
indications It is used to treat rhinitis and allergy symptoms.
contraindications Known hypersensitivity to this drug and severe hepatic disease prohibit its use. Its use is also contraindicated in lactating women and in newborn or premature infants.
adverse effects Life-threatening effects are hemolytic anemia, thrombocytopenia, leukopenia, agranulocytosis, pancytopenia, and arrhythmias (rare). Other adverse effects are urinary frequency, dysuria, urinary retention, impotence, thickening of bronchial secretions, dry nose and throat, nausea, diarrhea, abdominal pain, vomiting, constipation, headache, stimulation, drowsiness, sedation, fatigue, confusion, blurred vision, tinnitus, restlessness, tremors, paradoxical excitation in children or the elderly, rash, eczema, photosensitivity, urticaria, hypotension, palpitations, bradycardia, and tachycardia.