Robinow syndrome

(redirected from Fetal face)

Rob·i·now syn·drome

(rob'i-now), [MIM*180700]
a skeletal dysplasia characterized by bulging forehead, hypertelorism, depressed nasal bridge (so-called fetal face), wide mouth, acromesomelic shortening of limbs, hemivertebrae, and hypoplastic genitalia; there is also an autosomal recessive form [MIM*268310].
See also: fetal face syndrome.
Synonym(s): Robinow dwarfism

Robinow syndrome

An autosomal dominant disorder (OMIM:180700) characterised by short-limb dwarfism, costovertebral segmentation defects and malformations of the head, face and external genitalia.

Molecular pathology
Defects of WNT5A, which encodes a signalling molecule that regulates cell fate and patterning during embryogenesis, cause Robinow syndrome.

Rob·i·now syn·drome

(rob'i-now sin'drōm)
Skeletal dysplasia characterized by bulging forehead, hypertelorism, depressed nasal bridge (so-called fetal face), wide mouth, acromesomelic shortening of limbs, hemivertebrae, and hypoplastic genitalia; there is also an autosomal recessive form.

Robinow,

Meinhard, U.S. physician, 1909–.
Robinow dwarfism - Synonym(s): Robinow syndrome
Robinow mesomelic dysplasia
Robinow syndrome - dwarfism associated with several facial anomalies. Synonym(s): fetal face syndrome; Robinow dwarfism

Rob·i·now syn·drome

(rob'i-now sin'drōm) [MIM*180700]
Skeletal dysplasia characterized by bulging forehead, hypertelorism, depressed nasal bridge (so-called fetal face), and wide mouth.
References in periodicals archive ?
The obstetric ultrasound images of the fetal face demonstrate a single midline orbit (Figure 1).
They found that the movements of the fetal face become more complex over time.
Seventy-two international academics and clinicians contribute 33 chapters describing all aspects of the ultrasound diagnosis of fetal anomalies, including central nervous system malformations; normal/abnormal fetal face and neck; fetal echocardiography-diagnosed congenital cardiac problems; anomalies of the lungs, gastrointestinal tract and abdominal wall; urological tract diseases; and skeletal dysplasia.
Parents love to see 3-D images of the fetal face, which has led some nonmedical businesses to offer controversial "entertainment" 3-D ultrasound services in shopping malls and elsewhere.
This is particularly useful for imaging the fetal face and limbs to identify cleft palate, lips and other conditions during pregnancy.
One of those options is 3-D Fetal Face, popular among OB/GYN physicians, which provides easier identification of fetal abnormalities and allows expectant parents to view a photograph of their unborn child.
Advanced 3D/4D techniques can be helpful in examining a fetus for the presence of cataracts or cleft lip, or even a cleft palate--by obtaining a cross-sectional, reverse view of the fetal face.