fetal hemoglobin

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Related to Fetal blood: fetal hemoglobin

he·mo·glo·bin F

[MIM*142200]
normal fetal Hb (Hb F) of molecular formula α2Aγ2F, which is the major Hb component during intrauterine life, decreasing rapidly during infancy to reach a concentration of less than 0.5% in normal children and adults; the concentration of Hb F is increased in some hemoglobinopathies and in some cases of hypoplastic anemia, pernicious anemia, and leukemia; Hb F has a weaker affinity for 2,3-bisphosphoglycerate than does Hb A. More than 50 mutant variants of the γ chain have been reported.
Synonym(s): fetal hemoglobin

fetal hemoglobin

n.
The predominant form of hemoglobin in fetuses and newborn infants, present in small amounts in adults but often elevated in adults with certain forms of anemia and other disorders.

fetal hemoglobin

hemoglobin F, the major hemoglobin present in the blood of a fetus and neonate. Hemoglobin F is present in only trace amounts in the blood of normal adults.

fetal hemoglobin

Hemoglobin F An immature Hb composed of 2 α and 2 γ chains that usually disappears in the neonatal period. See Hereditary persistence of fetal hemoglobin.
References in periodicals archive ?
Richardson, "Placental compared with umbilical cord blood to assess fetal blood gas and acid-base status," Obstetrics and Gynecology, vol.
4] Laminated intervillous thrombi (linear streaks of fibrin with degenerating red and white blood cells in between) are thought to be caused by leakage of fetal blood into the intervillous spaces via defects in the trophoblast, usually occurring at varying times and leading to clotting of mixed fetal-maternal blood as a mechanism to limit fetal blood loss and fetomaternal bleeding.
Severe changes to the nervous tissue of fetus develop when the partial pressure of oxygen in the fetal blood decreases by 60-70% or more for 8-10 minutes (hypoxic encephalopathy).
In a letter to Sophie's parents in January 2015, Ken Bremner, Chief Executive of City Hospitals Sunderland NHS Foundation Trust, said: "It was not appropriate for fetal blood sampling to have been performed on a baby at 32 weeks gestation and that sampling caused an injury which caused Sophie's brain injury.
18 They showed that maternal anxiety levels had effects on the fetal blood flow.
This will include life-saving procedures such as fetal blood transfusions, laser treatment, bladder shunts and other procedures which are carried out at Liverpool Women's to save babies' lives in the womb - and sometimes those of their mothers.
Since the fetus gets its oxygen from the mother's blood, this condition leads to decreased oxygen in the fetal blood.
All staff now attend mandatory training sessions on electronic fetal monitoring and the use of fetal blood sampling.
During prenatal follow-up, no interventions, including fetal blood sampling or intrauterine transfusion, were performed.
The following diagnostic tools are important (Norwegian Institute of Public Health 2007; Norwegian Society of Gynecology and Obstetrics 2008): two-dimensional ultrasound, cardiotocography, STwaveform analysis (STAN) and fetal blood analysis.
Previous tests looked for a few fetal blood cells, perhaps 10 out of 200 billion in the sample, and those were fragile.