ferredoxins


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Related to ferredoxins: Adrenodoxin

fer·re·dox·ins

(fer'ĕ-dok'sinz),
Proteins containing iron-sulfur complexes and displaying electron-carrier activity but no classical enzyme function. Ferredoxins are found in green plants, algae, anaerobic bacteria, and in mitochondria from the adrenal cortex and heart muscle. They are involved in several oxidation-reduction reactions in living organisms (for example, nitrogen fixation).

fer·re·dox·ins

(fer'ĕ-dok'sinz)
Proteins containing iron and (labile) sulfur in equal amounts, displaying electron-carrier activity but no classical enzyme function. Ferredoxins are found in green plants, algae, and anaerobic bacteria, and are involved in several oxidation-reduction reactions in living organisms (e.g., nitrogen fixation).
References in periodicals archive ?
(11) announced the discovery of ferredoxin (Fd), a small iron-sulfur (FeS) protein of low redox potential, from Clostridium pasteurianum, and demonstrated it to be a physiological electron carrier for clostridial hydrogenase (reaction 1).
(2002) Genetic analysis of the archaeon Methanosarcina barkeri Fusaro reveals a central role for Ech hydrogenase and ferredoxin in methanogenesis and carbon fixation.
(2009) The iron hydrogenase of Thermotoga maritima utilizes ferredoxin and NADH synergistically: a new perspective on anaerobic hydrogen production.
Consistent with this idea, multiple hydrogenosomal fermentation enzymes--including ferredoxin, succinyl-CoA synthetase, and malic enzyme--resemble their counterparts in mitochondria (Johnson et al., 1990; Hrdy and Muller, 1995b).
An iron-dependent hydrogenase (Fe-hydrogenase), which gives the hydrogenosome its name, transfers electrons from reduced ferredoxin to two protons to make hydrogen gas (Lindmark and Muller, 1973; Muller, 1993; Payne et al., 1993; Bui and Johnson, 1996; Homer et al., 2000).
The reduced ferredoxin is produced within the hydrogenosome by pyruvate:ferredoxin oxidoreductase (PFOR), which decarboxylates pyruvate to acetyl-CoA and [CO.sub.2] (Lindmark and Muller, 1973; Muller, 1993; Payne et al., 1993; Hrdy and Muller, 1995a; Homer et al., 1999).
histolytica EST (GenBank AB002772), which encodes the N-terminus of a putative short Fe-hydrogenase 1, was identified from GenBank using BLASTP and an amebic 2[4Fe4S] ferredoxin sequence (Altschul et a!., 1997; Nixon et al., 2002).
lamblia genes encoding short Fe-hydrogenase, malic enzyme, alcohol dehydrogenase E (ADHE), and ferredoxin 1 (entamoebas only) (Rosenthal et al., 1997; Nixon et al., 2002).