Gestational diabetes: utility of fasting plasma glucose
as a screening test depends on the diagnostic criteria.
Table 2: Pearson's correlation as measured between eAG with age, fasting plasma glucose
Fasting plasma glucose
was estimated by GOD/POD (glucose oxidase-peroxidase) method.
To summarize, the metabolic factors noted in our study including central obesity, raised HDL, raised cholesterol, raised blood pressure and raised fasting plasma glucose
level are comparable with the findings of majority of the above mentioned studies.
During 2011-2012, the prevalence of diabetes based on 2-hour postprandial glucose, fasting plasma glucose
, or hemoglobin A was 14.3% for total diabetes (diagnosed and undiagnosed).
The quantitative insulin sensitivity check index (QUICKI) was calculated from fasting plasma glucose
([G.sub.o] in mg/dL) and insulin ([I.sub.o] in [micro]IU/mL) concentrations, as follows: QUICKI = 1/(log [I.sub.o] + log [G.sub.o]) (Radikova 2003)
Most of the insulin resistant patients were postmenopausal but, interestingly, most of them had fasting plasma glucose
and/or fasting plasma levels in the normal range.
The prevalence of the metabolic syndrome was also assessed according to the ATP III criteria; when three or more of the following five conditions were present: abdominal obesity (waist circumference [greater than or equal to] 102 cm in men, [greater than or equal to] 88 cm in women); serum triglycerides equal to or greater than 150 mg/dl; HDL cholesterol less than 39 mg/dl in men; systolic blood pressure equal to or greater than 130 mm Hg and/or diastolic blood pressure equal to or greater than 85 mm Hg; and fasting plasma glucose
110 mg/dl or greater.
Inclusion criteria were (1) newly diagnosed T2D patients according to WHO criteria , (2) age from 40 to 70 years old, (3) antidiabetic drug naive, (4) mean (of two) fasting plasma glucose
(FPG) measurements from 7 to 11mmol/L, and (5) glycosylated hemoglobin (HbA1C) from 7 to 9%.
Overnight fasting blood samples were collected for the determination of fasting plasma glucose
(FPG), HbA1c, fasting insulin (FINS), triglyceride (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-c), low-density lipoprotein cholesterol (LDL-c), and liver and kidney functions.
The reciprocal index of homeostasis model assessment (HOMA) was calculated as the product of fasting plasma glucose
(mg/dL) by plasma insulin (mU/L), divided by a constant (405), as a measure of insulin resistance (9).
Higher normal fasting plasma glucose
is associated with hippocampal atrophy: the PATH Study.