Gardner's syndrome

(redirected from Familial Polyposis Coli)
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Gardner's syndrome

 [gahrd´nerz]
familial polyposis of the colon associated with osseous and soft tissue tumors.

Gardner's syndrome

An autosomal dominant hereditary disorder featuring multiple benign bony tumours (osteomas), EPIDERMOID CYSTS, soft tissue tumours including DESMOID TUMOURS, POLYPS in the intestine, and a 95% chance of developing cancer of the colon. (Eldon John Gardner, American geneticist, b. 1909).
References in periodicals archive ?
Desmoid tumors in familial polyposis coli. Ann Surg 1986;204-94-7.
Four of Patricia's five sisters inherited the tragic genetic legacy of familial polyposis coli which can lead to colon cancer.
"With the exception of presymptomatic testing for familial polyposis coli [a genetic disorder resulting in colon cancer], there is no documented benefit to the child of testing for cystic fibrosis carrier status or presymptomatic testing for Huntington's disease."

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