thrombin

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Related to Factor II deficiency: Factor V deficiency

thrombin

 [throm´bin]
1. the activated form of coagulation factor II (prothrombin), which catalyzes the conversion of fibrinogen to fibrin.
2. a preparation of this compound prepared from prothrombin of bovine origin, used as a topical hemostatic.
thrombin time (TT) the time required for plasma fibrinogen to form thrombin: exogenous thrombin is added to citrated plasma and the time to clot formation is measured. Prolonged TT is seen with abnormalities of fibrinogen and in the presence of heparin or degradation products of fibrin or fibrinogen.

throm·bin

(throm'bin),
1. An enzyme (proteinase), formed in shed blood, that converts fibrinogen into fibrin by hydrolyzing peptides (and amides and esters) of l-arginine; formed from prothrombin by the action of prothrombinase (factor Xa, another proteinase).
2. A sterile protein substance prepared from prothrombin of bovine origin through interaction with thromboplastin in the presence of calcium; causes clotting of whole blood, plasma, or a fibrinogen solution; used as a topical hemostatic for capillary bleeding with or without fibrin foam in general and plastic surgical procedures.

thrombin

(thrŏm′bĭn)
n.
A protease in blood that facilitates blood clotting by converting fibrinogen to fibrin.

thrombin

Hematology A key clot promoting enzyme that converts fibrinogen to fibrin and protects against fibrinolysis by activating thrombin-activatable fibrinolysis inhibitor. See Fibrin, Fibrinolysis, TAFI.

throm·bin

(throm'bin)
1. An enzyme (proteinase), formed in shed blood, that converts fibrinogen into fibrin by hydrolyzing peptides (and amides and esters) of l-arginine; formed from prothrombin by the action of prothrombinase (factor Xa, another proteinase).
2. A sterile protein substance prepared from prothrombin of bovine origin through interaction with thromboplastin in the presence of calcium; causes clotting of whole blood, plasma, or a fibrinogen solution; used as a topical hemostatic for capillary bleeding with or without fibrin foam in general and plastic surgical procedures.
Synonym(s): factor IIa.

thrombin

An enzyme in the blood that converts fibrinogen to fibrin, thus forming a blood clot.

thrombin

see BLOOD CLOTTING.

Thrombin

Thrombin is a protein produced by the body. It is a specific clotting factor that plays an important role in the blood clotting process.

throm·bin

(throm'bin)
1. An enzyme (proteinase), formed in shed blood, which converts fibrinogen into fibrin by hydrolyzing peptides (and amides and esters) of l-arginine; formed from prothrombin by the action of prothrombinase.
2. A sterile protein substance prepared from prothrombin of bovine origin through interaction with thromboplastin in the presence of calcium; causes clotting; used as a topical hemostatic for capillary bleeding in general and plastic surgical procedures.
Synonym(s): factor IIa.