Fab therapy

Fab therapy

Therapeutics The use of antibody fragments–Fab fractions against certain antigens–eg, digoxin, to treat dioxin overdose. See Fab fragment, Psoriasis.
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Although digoxin immune Fab therapy may function similarly in a patient with decreased renal function, neither digoxin nor Fab can be removed by hemodialysis which was believed that it would complicate the removal of toxins and anesthesia further in this case [8].
Such compounds would be extracted from tissue stores by Fab therapy and are likely to interfere with digoxin immunoassays, depending on the corresponding affinity of and reactivity with capture antibodies.
Pharmacokinetic aspect of digoxin-specific Fab therapy in the management of digitalis toxicity.