Fab fragment(redirected from Fab piece)
the antigen-binding fragment of an immunoglobulin molecule, containing the variable regions of both light and heavy chains.
Synonym(s): Fab piece
Fab frag·ment(fab frag'mĕnt)
The antigen-binding fragment of an immunoglobulin molecule, consisting of both a light chain and part of a heavy chain.
Area on an immunoglobulin (antibody) to which antigens bind. The enzyme papain splits antibodies into three fragments, two Fab fragments, each of which is antigen-specific, and an Fc or crystallizable fragment, which is involved in secondary antibody activities such as activating complement.
See also: fragment
a portion of an immunoglobulin molecule usually obtained by papain digestion, containing one light chain and part of a heavy chain with a single antigen-combining site.