FOXF1

A gene on chromosome 16q24 that encodes a member of the forkhead family of transcription factors, which may play a role in embryonic development and in regulating lung-specific genes.

References in periodicals archive ?

Likewise, failures in the expression of HNF6, HNF1b or Foxf1 result in alterations in the development of the gallbladder and the common bile duct.

Biliary Tract in Trident, an Anatomical Variation Between the Cystic Duct and its Union to the Common Hepatic Duct. A Rare Case Report/ Tracto Biliar en Tridente, una Variacion Anatomica Entre el Conducto Cistico y su Union al Conducto Hepatico Comun. Un Caso Raro

(2015), siliyopati ile iliskili 25 aday genin hedefe yonelik YND ile yaptiklari calismada, 4 olguda ZIC3 geninde, 1 olguda ise FOXF1 geninde mutasyon saptamistir.

RADIYAL ISIN DEFEKTLERININ KLINIK SINIFLANDIRMASI VE ETYOPATOGENEZININ ARASTIRILMASI/CLINICAL CLASSIFICATION OF RADIAL RAY DEFECTS AND RESEARCH INTO ETIOPATHOGENESIS

determined that ARPC2 was regulated by Forkhead box F1 (FOXF1) and might be involved in cell growth of lung fibroblasts [12].

Role of ARPC2 in Human Gastric Cancer

Recently FOXF1 abnormalities were detected in up to 70% of ACD/MPV cases; however, the exact mechanism through which these genetic abnormalities lead to ACD/MPV is yet to be elucidated [5].

All ACD/MPV patients were tested for mutation in FOXF1 and 4 were tested for rearrangements at 16q24 locus.

The Role of Serotonin Transporter in Human Lung Development and in Neonatal Lung Disorders

Petrou et al., "Expression of bmi1, FoxF1, nanog, and y-catenin in relation to hedgehog signaling pathway in human non-small-cell lung cancer," Lung, vol.

The Hedgehog Signaling Networks in Lung Cancer: The Mechanisms and Roles in Tumor Progression and Implications for Cancer Therapy

(62) Recently, it was reported that the activities of CAFs in lung cancer are regulated by Forkhead Box F1 (FoxF1), (63) a member of the FOX transcription factor family.

Discovery of cytoglobin and its roles in physiology and pathology of hepatic stellate cells

These examples of honeycomb lung show distinct epithelial expression of FoxF1 and SSH proteins, gene products that have a role in lung development.

Honeycomb Lung: Time for a Change

FOXF1 FOXF1 has high expression in normal prostate and its expression decreases in prostate cancer (39).

Comparative analysis of prostate cancer gene regulatory networks via hub type Variation

The p53-p21WAF1 checkpoint pathway plays a protective role in preventing DNA replication induced by abrogation of FOXF1 function.

[beta]-Asarone induces senescence in colorectal cancer cells by inducing lamin B1 expression

(12) Recientemente, se han identificado microdelecciones del grupo de genes FOX en 16q24.1, que consta de cuatro genes, FOXF1, MTHFSD FOXC2, y FOXL1, como causantes de un fenotipo parecido a la asociacion VACTERL, con anomalias vertebrales, atresias gastrointestinal (esofago, duodeno o ano), cardiopatias congenitas y malformaciones del tracto urinario, asi como una rara anomalia letal de desarrollo del pulmon, la displasia capilar alveolar.

Presentacion de un caso con multiples malformaciones congenitas: asociacion VACTERL / a case with multiple congenital malformations: VACTERL association

The disease that usually kills the infants born with it within the first month of life results from deletions or mutations in the FOXF1 transcription factor gene, said a consortium of researchers led by Baylor College of Medicine (www.bcm.edu) in a report that appears in the American Journal of Human Genetics.

Gene for deadly inherited lung disease identified

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