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A gene on chromosome 14q24.3 that encodes a leucine zipper DNA-binding FOS-type nuclear phosphoprotein, which dimerises with proteins of the JUN family to form the transcription factor complex AP1. FOS proteins regulate cell proliferation, differentiation and transformation, and may be associated with apoptosis.


A family of cancer-causing genes, first identified in viruses, that function within cells as transcription factors. Members of this family can transform normal cells (e.g., fibroblasts) into cancer cells (e.g., osteosarcomas, chondrosarcomas). See: oncogene; transformation


The name is derived from “FBJ osteosarcoma virus, ” in which these oncogenes were first identified.

References in periodicals archive ?
With PPI mis-selling being widespread there is a large volume of PPI-related complaints being received by the FOS, but the bank's delaying tactics are playing a role too.
Later this year, FOS students will have the opportunity to reinforce their classroom learning with some new distance learning offerings.
Upping the Ombudsman award into big-money cases raises important issues about the quality of justice on offer through the FOS.
In one technique, the bougie was passed down the right side of the airway space by one operator while another operator passed a paediatric FOS down the left side to direct placement of the bougie into the trachea.
F+M FOS exhibited at the gulfBid 2009 exhibition in Bahrain this May and received a great response for its creations.
Mounted and dismounted patrols; area-of-operations presence patrols; and aggressive shows of force synchronizing direct, indirect, and aerial fires were executed to prevent ACM attacks or infiltration via the FOS.
Yogurts made with a FOS of from DP 3 to DP 5 and inulin had significantly less syneresis than the control.
The original FOS was developed to assess adults' retrospective perceptions of their family of origin.
FOS is taking steps to rectify the oversupply situation and put the industry back on a profitable footing.
Additionally, the latest consumption of FOS in China is charted with forecasts provided for the coming years.
This approach is based on consistent application of the FOS approach and is scrutinised by ASIC and Deloitte.
Key Topics Covered: Chapter One FOS Industry Overview Chapter Two FOS International and China Market Analysis Chapter Three FOS Development Environmental Analysis Chapter Four FOS Development Policy and Plan Chapter Five FOS Manufacturing Process and Cost Structure Chapter Six 2009-2014 FOS Productions Supply Sales Demand Market Status and Forecast Chapter Seven FOS Key Manufacturers Analysis Chapter Eight Up and Down Stream Industry Analysis Chapter Nine FOS Marketing Channels Analysis Chapter Ten FOS Industry Development Trend Chapter Eleven FOS Industry Development Proposals Chapter Twelve FOS New Project Investment Feasibility Analysis Chapter Thirteen Global and China FOS Industry Research Conclusions Companies Mentioned: