FGF13

FGF13

A gene on chromosome Xq26.3 that encodes fibroblast growth factor 13 of the FGF family, which bind heparin and have a broad range of cellular activities, including cell survival, division, differentiation and migration, embryonic development, morphogenesis, tissue repair, tumour growth and invasion. FGF13’s function is unknown; it is thought to play a role in nervous system development and function.

Molecular pathology
FXF13 is a candidate gene for Borjeson-Forssman-Lehmann syndrome.
References in periodicals archive ?
Tuberous sclerosis 2 (TSC2), phosphatase and tensin homolog (PTEN), PIK3CA, and fibroblast growth factor 13 (FGF13) are among the key modulators of the mTOR pathway [98, 99].
The coding gene for miR504 is in the third intron of the Fgf13 gene on the X chromosome.
Regulation of actin GNG12, SSH2, BRAF, FGF13, PAK7, et al.
In a recent study, Lea et al (2009) showed that FGFI, FGF3, FGF13, FGFI4, and FGF20 are expressed during embryonic eye development in Xenopus tropicalis.