FGF13 | definition of FGF13 by Medical dictionary
FGF13 A gene on chromosome Xq26.3 that encodes fibroblast growth factor 13 of the FGF family, which bind heparin and have a broad range of cellular activities, including cell survival, division, differentiation and migration, embryonic development, morphogenesis, tissue repair, tumour growth and invasion. FGF13’s function is unknown; it is thought to play a role in nervous system development and function.
FXF13 is a candidate gene for Borjeson-Forssman-Lehmann syndrome.
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References in periodicals archive
Tuberous sclerosis 2 (TSC2), phosphatase and tensin homolog (PTEN), PIK3CA, and fibroblast growth factor 13 (FGF13
) are among the key modulators of the mTOR pathway [98, 99].
The coding gene for miR504 is in the third intron of the Fgf13
gene on the X chromosome.
Regulation of actin GNG12, SSH2, BRAF, FGF13
, PAK7, et al.
In a recent study, Lea et al (2009) showed that FGFI, FGF3, FGF13
, FGFI4, and FGF20 are expressed during embryonic eye development in Xenopus tropicalis.