* Lipid Bilayer-based Carriers loaded with Polypeptide Growth Factors: sh-Oligopeptide-1 (EGF), -4(Thymosin-b4); sh-Polypeptide-1 (FGF2), -3(FGF7), -4(SCF), -5(TGFb3), -7(hGH), -9(VEGF), -10(
FGF10), -11(FGFl), -15(TIMP2), -22(TGFbl), -28(PRL), -40(hPL), -59(PDGF), -71 (VIP), -78(HSP90A), -93(CTGF), -101 (Adiponectin)
Fgf10 has been reported to participate in adipogenesis.
Enhanced paracrine
FGF10 expression promotes formation of multifocal prostate adenocarcinoma and an increase in epithelial androgen receptor.
Govindarajan et al., "
FGF10 is an inducer and Pax6 a competence factor for lacrimal gland development," Development, vol.
FGF3 and
FGF10 have some form of functional redundancy, as Fgf3-/- or Fgf10-/- mice develop teeth normally, but mice that lack the FgfR2b receptor (the receptor for Fgf3 and
Fgf10) exhibit teeth that arrest at the bud stage [Zhang et al., 2005].
Washington, July 16 (ANI): Scientists at the Salk Institute for Biological Studies have found that a growth factor called
Fgf10 helps keep the brain's development on track.
Human lung fibroblasts were exposed to various concentrations of 2,4-D, MCPA, FGF 1, FGF6 and
FGF10. Two controls were used: no cells, and solvent solution.
FGF2 and
FGF10 are also expressed in adipose tissue and have each been implicated in adipogenesis.
FGF10 inhibits dominant follicle growth and estradiol secretion in vivo in cattle.
The
FGF10 is firstly expressed in the formative period of mammary line and regulates FGFR2b to affect Wnt10 response to the development of the mammary line.
Stijn De Langhe, Ph.D., and his colleagues reported that destruction of lung tissue in mice induces smooth muscle cells surrounding the airways to secrete a protein known as fibroblast growth factor 10 (
FGF10), which induces surviving epithelial cells in the airways to revert to a stem-cell state, proliferate, repair and repopulate the lining of die lungs.