FFPE


Also found in: Acronyms.

FFPE

formalin-fixed, paraffin-embedded.
References in periodicals archive ?
Encouraged by these validation studies, researchers began to apply HTS miRNA-seq to FFPE specimens [84, 85].
Nonfrozen, formalin-fixed specimens or FFPE blocks are the preferred sample type for histopathologic evaluation and immunohistochemistry, and RT-PCR can be performed on either fresh frozen or formalinfixed specimens.
In contrast to 16S specimens, ITS had a much larger proportion of FFPE tissues.
Several commercial kits specifically designed for nucleic acid extraction from FFPE tissue specimens have been recently introduced to the market and are gradually being used in research on FFPE (11, 12).
Of the 50 FFPE tissue blocks evaluated, 43 (86%) were cHL and 7 (14%) were NLPHL.
high-risk profiles were obtained, irrespective of whether fresh tumour biopsies or FFPE tissue was used.
To help control for the variability encountered in other genomic studies, the present study performed microarray analysis utilizing FFPE stored liver tissue among a select group of patients, mostly male Caucasians with an average age of 55 years.
Rubicon's TransPLEX RNA kits and GenomePLEX[R] DNA kits are members of its OmniPLEX[R] family of amplification technologies that are designed to deliver sufficient quantities of high quality nucleic acids to enable analyses of FFPE samples for biomedical research and clinical medicine.
For DNA preparation from FFPE tissues, 8-10 consecutive sections were subjected to deparaffinization, tissues were then lysed by proteinase K, and DNA was purified by phenol-chloroform extraction.
This partnership enables researchers in India, for the first time, to conduct gene expression profiling from a wide range of clinically relevant sample types, such as small, compromised, or formalin-fixed, paraffin-embedded (FFPE) tissues.
Until now, researchers thought that this formalin-fixed, paraffin-embedded (FFPE) preservation process destroyed, modified, or degraded the nucleic acids, specifically the DNA and RNA, in biopsy samples, precluding gene expression analysis.
The apparatus is capable of producing high quality, uniform and reproducible immunohistochemical staining (ihc) for both formalin-formalized paraffin-embedded specimens (ffpe) and ice sheets.