NLRP3

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NLRP3

A gene located on chromosome 1q44 that encodes a pyrin-like protein that interacts with the apoptosis-associated speck-like protein PYCARD/ASC. NLRP3 has a caspase recruitment domain, and belongs to the NALP3 inflammasome complex; it plays a role in regulating inflammation and apoptosis.
 
Molecular pathology
NLRP3 mutations are associated with chronic infantile neurological cutaneous and articular (CINCA) syndrome, familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome and neonatal-onset multisystem inflammatory disease (NOMID).
References in periodicals archive ?
The FCA intends ensure that financial promotion rules are media-neutral and that consumers are given certain minimum information, in a fair and balanced way.
Hensoldt is convinced that the combination of the outstanding individual competences in the areas of sensors, effectors, communication and mission systems within this consortium will provide valuable contributions to fulfil the operational needs of the FCAS programme on sensor/effector mission system level.
The Economic Secretary to the Treasury, John Glen, has approved the FCAs appointment of Dame Elizabeth Gloster to lead the investigation and has laid before Parliament the direction to initiate this work.
FCAs rose by USD 341.4 million to USD 336.187 billion in the week under review, an RBI release said.
British financial service industry regulator the Financial Conduct Authority (FCA) announced on Tuesday that its interim report into the effectiveness of competition in the cash savings market has shown that UK banks pay lower interest rates to customers who do not shop around for easy-access deposit accounts.
FCAs, expressed in dollar terms, include the effect of appreciation and depreciation of non-US currencies, such as the euro, pound and the yen, held in the reserves.
VPPs can provide increasingly valuable market services such as frequency control, reactive power and voltage control (FCAS).
Mumbai: Country's foreign exchange reserves declined by a whopping USD 3.58 billion to USD 346.79 billion in the week ended February 26, on account of fall in foreign currency assets (FCAs), according to Reserve Bank.
Ex pov is a 10,000,000 7 year (84 months) programme that intends to procure technical assistance to provide research and evaluation to help dfid and its partners to better understand the changing nature of global extreme poverty and use this to deliver dfids core business, supporting more effective strategies, policies and programmes for poverty reduction in particular in fragile and conflict-affected states and situations (fcas).There is the possibility of a 42 month extension and/or up to 5,000,000.
Mumbai: Country's foreign exchange reserves rose by USD 347.2 million to USD 351.831 billion in the week to February 12, helped by an increase in foreign currency assets (FCAs), according to the Reserve Bank.
Ex Pov is a 10 000 000 GBP 7-year (84 months) programme that intends to procure technical assistance to provide research and evaluation to help DFID and its partners to better understand the changing nature of global extreme poverty and use this to deliver DFID's core business, supporting more effective strategies, policies and programmes for poverty reduction in particular in fragile and conflict-affected states and situations (FCAS).
Accordingly, this figure will be the total number of voting rights in the Company and may be used by Shareholders as the denominator for the calculations by which they determine if they are required to notify their interest in, or change to their interest in, the Company under the FCAs Disclosure Guidance and Transparency Rules.