BPTF

(redirected from FAC1)

BPTF

A gene on chromosome 17q24.3 that encodes a histone-binding component of nucleosome-remodelling factor (NURF), a protein complex which catalyses ATP-dependent nucleosome sliding and facilitates transcription.

Molecular pathology
High levels of FAC1/BPTF may be found in foetal brain and in patients with neurodegenerative diseases (e.g., Alzheimer’s disease).
References in periodicals archive ?
A significant increase (p<0.05) was observed in Fac1 ([DELTA] = 15.20%), Fac2 ([DELTA] = 30.43%), Fac4 ([DELTA] = 14.90%), Fac5 ([DELTA] = 35.54%), and TS ([DELTA] = 18.79%) in REG in relation to pre-test.
Coeficientes [[beta].sub.LIPT-45] para la prediccion del bienestar psicologico Factores componentes del LIPT-45 B Error Wald estandar FAC1 (Comprometer su salud) -,132 ,063 4,431 FAC2 (Limitar su contacto social) -,140 ,065 4,630 FAC3 (Desacreditar su capacidad profesional y laboral) -,336 ,062 29,472 FACA (Limitar su comunicacion) -,484 ,068 51,306 FAC5 (Desprestigiarlo ante sus companeros) -.248 ,060 17,035 Constante 2,109 ,083 642,273 Factores componentes del LIPT-45 gl Sig.
Bioinformatic analyses indicated that rs1885301 is situated 5' of the promoter and that the G > A substitution results in loss of one transcription-factor binding site [Fetal Alz-50 clone 1 (FAC1)] and gain of another site (FAST-1 SMAD interacting protein).
1-1 11,615 12 (A) Swindon (FAC1) Novak .......................
% 1 0.8832 0.9301 93.008 6.992 2 0.8708 0.9102 91.020 8.980 3 0.8866 0.8896 88.956 11.044 4 0.5786 0.8967 89.672 10.328 5 0.4080 0.2486 24.860 75.140 Rotated Factor Matrix Fac1 Fac2 1 0.9643 * -0.0119 2 0.8752 * 0.3798 3 0.9414 * 0.0575 4 0.0451 0.9460 * 5 0.0845 0.4913 Var.
Where: FAC1 = Reliability; FAC2 = Access; FAC3 = Ease of use; FAC4 = Personalization; FAC5 = Credibility; FAC6 = Security; fac1 = Security; fac2 = Responsiveness; fac3 = Ease of Use; fac4 = Availability; fac5 = Reliability; fac6 = Personalization; fac7 = Access; Edu = Education Levels; [SQ.sub.p] = Internet Purchasers' Perceived Overall Service Quality; [SQ.sub.NP] = Internet non-purchasers' Perceived Overall Service Quality; and [[beta].sub.1] and [[gamma].sub.1] represent the parameters to be estimated.
Breast Hormone 30 -1 Breast FAC1 50-80 -1 Ovarian Taxane-platinum 60 -2 Testicular Platinum regime 80 -3 Colorectal 5FU + LV 20 -4 (a) FAC, fluorouracil, doxorubicin, and cyclophosphamide; 5FU + LV, 5-fluorouracil + leucovorin.