FABP5


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FABP5

A gene on chromosome 8q21.13 that encodes a lipid transport protein in epidermal cells which may be involved in keratinocyte differentiation. FABP5 binds fatty acids and has the highest affinity for C18 length chains; it is upregulated in psoriasis.
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For example, PCK1, PLIN4, and FABP5 were all increased to a greater extent by TPP.
Among Fabps, Fabp3 (H-Fabp), Fabp5 (E-Fabp, KFabp, or S-Fabp) and Fabp7 (BLBP or B-Fabp) are the members expressed in the brain.
The antibodies in human FABP4 ELISA are highly specific for human FABP4, with no detectable cross-reactivity to human FABP1, FABP2, FABP3, or FABP5.