FABP4

FABP4

A gene on chromosome 8q21 that encodes a lipid transport protein in adipocytes which plays a role in intracellular transport of long-chain fatty acids and retinoic acids, delivering them to their cognate receptors in the nucleus.
References in periodicals archive ?
For the experiment, a fatty acid-binding protein called "4 (fabp4)" was targeted.
Similarly, mRNA and protein levels of adipogenesis markers such as CCAAT enhancer binding protein beta (C/EBP[beta]), peroxisome proliferator activated receptor gamma (PPAR[gamma]), and fatty acid binding protein 4 (FABP4) were significantly higher in Mashen pigs than in Large White pigs.
Researchers gave healthy, normal-weight mice a dose of the preservative and found that it activated the sympathetic nervous system and increased the levels of the hormones glucagon and FABP4, which are normally elevated only when a person is fasting.
Fatty acid binding protein 4, fabp4, causes impaired wound healing in diabetes.
Several key factors that regulate lipogenesis and lipolysis (including fatty acids binding proteins (FABP4 and FABP5) (Boucher et al.
Primers synthesized by Invitrogen for collagen type I (Col1A1), osteonectin (ON), collagen type II (Col2A1), aggrecan (ACAN), and fatty-acid-binding protein-4 (FABP4) were used in this study (Table 2).
Cells were then incubated with the following primary antibodies: anti-human CD29 monoclonal antibody, anti-human CD166 monoclonal antibody (BioLegend, San Diego, CA, USA), anti-human CD34 monoclonal antibody (BD Biosciences), and goat anti-mouse FABP4 antibody (R&D Systems).
The adipogenic genes CEBPa and FABP4 were up-regulated in the sucralose-exposed MSCs, which also showed more intracellular fat droplet accumulation.
Implications of circulating irisin and Fabp4 levels in patients with polycystic ovary syndrome.
Other glycated proteins such as glycated fibronectin and glycated pregnancy-specific glycoprotein (PSG), glycated complement regulatory protein CD59, plasma fatty acid binding protein 4 (FABP4), plasma retinol binding protein 4 (RBP4), and plasma adipocytokine are being investigated for their potential to diagnose GDM without the need for fasting and oral glucose administration.
After 21 days, adipocytes, osteocytes, and chondrocytes were detected using immunocytochemistry staining for FABP4, osteocalcin, and aggrecan, respectively.
Meana et al., "Altered CSNK1E, FABP4 and NEFH protein levels in the dorsolateral prefrontal cortex in schizophrenia," Schizophrenia Research, vol.