FABP3

Also found in: Acronyms.

FABP3

A gene on chromosome 1p33-p32 that encodes a fatty acid-binding protein thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP3 plays a role in arresting growth of mammary epithelial cells and is a candidate tumour suppressor gene for breast cancer.

References in periodicals archive ?

In the same study [3], FABP3 was the second most abundant transcript with a nearly 80-fold change in transcript abundance at 60 days of lactation.

Also, three of the four genes showing the maximum relative change in expression, namely, FABP3, CD36, and XDH, were chiefly under the control of PPARG.

Electronic Northern Analysis of Genes and Modeling of Gene Networks Underlying Bovine Milk Fat Production

Loor, "ACSL1, AGPAT6, FABP3, LPIN1, and SLC27A6 are the most abundant isoforms in bovine mammary tissue and their expression is affected by stage of lactation," The Journal of Nutrition, vol.

PPAR[gamma] regulates genes involved in triacylglycerol synthesis and secretion in mammary gland epithelial cells of dairy goats

The AKR1C1, HMGCS2, and FABP3 genes are associated with regulation of rumen development during early weaning.

Overexpression of FABP3 inhibits human bone marrow derived mesenchymal stem cell proliferation but enhances their survival in hypoxia.

Early weaning of calves after different dietary regimens affects later rumen development, growth, and carcass traits in Hanwoo cattle

FABP3 is involved in the uptake, transport, and metabolism of fatty acids (FAs) and is mainly expressed in cardiac and skeletal muscle.

Whereas, the FABP3 gene had a negative relationship according to PC1.

Gene expression patterns associated with peroxisome proliferator-activated receptor (PPAR) signaling in the longissimus dorsi of Hanwoo (Korean cattle)

FASN, ACACA, and FABP3 mRNA expressions in BMECs were significantly (p<0.05) down-regulated linearly or quadratically with the addition of palmitate (Table 4), and treatments with addition of 500 to 600 [micro]M palmitate had lower FASN, ACACA mRNA expressions than the control and those with addition of 200 to 400 [micro]M palmitate.

Effects of saturated long-chain fatty acid on mRNA expression of genes associated with milk fat and protein biosynthesis in bovine mammary epithelial cells

TZD supplementation resulted in an up-regulation of FABP3 expression (a 65.12% increase in mRNA abundance, p<0.10).

Effects of dietary thiazolidinedione supplementation on growth performance, intramuscular fat and related genes mRNA abundance in the longissimus dorsi muscle of finishing pigs

Effects of ADCYP1R1, FABP3, FABP4, MC4R, MYL2 genotypes on growth traits in F2 population between Landrace and Jeju native black pig.

Comparison of live performance and meat quality parameter of cross bred (Korean native black pig and landrace) pigs with different coat colors

In addition, a set of genes including GHR, MC1R, FABP3, CLPN3, SPERT, HTR2A5, ABCE1, BMP4 and PTGER2 were possibly subject to selective sweeps (Flori et al., 2009; Qanbari et al., 2010a).

Development and application of high-density SNP arrays in genomic studies of domestic animals

Expression of FABP1 was much greater in liver, while FABP3 and FABP4 transcripts were much more abundant in mammary tissues.