FABP3


Also found in: Acronyms.

FABP3

A gene on chromosome 1p33-p32 that encodes a fatty acid-binding protein thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP3 plays a role in arresting growth of mammary epithelial cells and is a candidate tumour suppressor gene for breast cancer.
References in periodicals archive ?
In the same study [3], FABP3 was the second most abundant transcript with a nearly 80-fold change in transcript abundance at 60 days of lactation.
Also, three of the four genes showing the maximum relative change in expression, namely, FABP3, CD36, and XDH, were chiefly under the control of PPARG.
Loor, "ACSL1, AGPAT6, FABP3, LPIN1, and SLC27A6 are the most abundant isoforms in bovine mammary tissue and their expression is affected by stage of lactation," The Journal of Nutrition, vol.
The AKR1C1, HMGCS2, and FABP3 genes are associated with regulation of rumen development during early weaning.
Overexpression of FABP3 inhibits human bone marrow derived mesenchymal stem cell proliferation but enhances their survival in hypoxia.
FABP3 is involved in the uptake, transport, and metabolism of fatty acids (FAs) and is mainly expressed in cardiac and skeletal muscle.
Whereas, the FABP3 gene had a negative relationship according to PC1.
FASN, ACACA, and FABP3 mRNA expressions in BMECs were significantly (p<0.05) down-regulated linearly or quadratically with the addition of palmitate (Table 4), and treatments with addition of 500 to 600 [micro]M palmitate had lower FASN, ACACA mRNA expressions than the control and those with addition of 200 to 400 [micro]M palmitate.
Effects of ADCYP1R1, FABP3, FABP4, MC4R, MYL2 genotypes on growth traits in F2 population between Landrace and Jeju native black pig.
In addition, a set of genes including GHR, MC1R, FABP3, CLPN3, SPERT, HTR2A5, ABCE1, BMP4 and PTGER2 were possibly subject to selective sweeps (Flori et al., 2009; Qanbari et al., 2010a).
Expression of FABP1 was much greater in liver, while FABP3 and FABP4 transcripts were much more abundant in mammary tissues.