[5] Nonstandard abbreviations: AKI, acute kidney injury; GFR, glomerular filtration rate; AKIN, Acute Kidney Injury Network; IL, interleukin; NGAL, neutrophil gelatinase-associated lipocalin; KIM-1, kidney injury molecule 1; MIOX and Miox, myo-inositol oxygenase; cRNA, complementary RNA; GST, glutathione S-transferase; rMIOX, recombinant MIOX; BLAST, basic local alignment search text; H&E, hematoxylin and eosin;
FABP1, liver type fatty acid-binding protein 1.
It has been observed that human liver-and heart-type FABP (FABP1 and FABP3) are expressed in the proximal and distal renal tubular cells, respectively (14, 15), and increased amounts of FABP1 in urine have been postulated as a clinical marker of renal tubulointerstitial damage (16, 17).
The antibodies in human FABP4 ELISA are highly specific for human FABP4, with no detectable cross-reactivity to human FABP1, FABP2, FABP3, or FABP5.