FBXW12(redirected from F-box- and WD-40 domain-containing protein 12)
FBXW12A gene on chromosome 3p21.31 that encodes a so-called F-box protein, which contains a 40 amino acid protein-interacting motif (the F box). F-box proteins form a complex with SKP1 and cullin, resulting in phosphorylation-dependent ubiquitination and ubiquitin-mediated degradation of targeted proteins.
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