extramammary Paget's disease


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extramammary Paget's disease

[-mam′ərē]
Etymology: L, extra, outside, mamma, breast; James Paget, English surgeon, 1814-1899; L, dis + Fr, aise, ease
a gradually spreading red, scaly, and crusted lesion resembling that of Paget's disease but not occurring on the breast. A common area is the vulva. The lesions give rise to carcinoma in approximately 50% of the cases.

extramammary Paget's disease

 A lesion similar to Paget's disease of breast, less often linked to underlying malignancy; the condition arises from skin adnexae, visceral malignancy or rarely, de novo, in scrotum, perineum, labia majora; cells are more often mucin-positive than in Paget's disease of breast
References in periodicals archive ?
2 and BerEP4 positivity in pagetoid squamous cell carcinoma in situ (pagetoid Bowen's disease) of the perianal region: A mimic of extramammary Paget's disease.
12] The differential diagnoses of Hailey-Hailey disease included fungal infection, intertrigo, psoriasis, extramammary Paget's disease, acanthosis nigricans, pemphigus vegetans and Darier's disease.
Extramammary Paget's disease of the penis with features of Bowen's disease.
Vulvar clear cells of Toker: precursors of extramammary Paget's disease.
Extramammary Paget's disease (EMPD) is a rare skin disease and amongst which the EMPD of the scrotum is the commonest.
Skin conditions with a similar appearance to lichen simplex chronicus include lichen planus, lichen sclerosus, psoriasis, mycosis fungoides, and extramammary Paget's disease.
Extramammary Paget's disease (EMPD) is a rare neoplasm with only a limited number of reported cases in literature.
These include morpheaform BCC, squamous cell carcinoma, lentigo maligna of the face (associated with a recurrence rate of 10% to 20% following surgery alone (6)), and extramammary Paget's disease (recurrence rate of 40% after surgery alone (6)), In addition, topical imiquimod may be helpful for reducing the 50% rate of recurrence following surgical excision of keloids.
Extramammary Paget's disease is most often found in the vulvar area and usually has an excellent prognosis, Peter J.
Cytokeratin 7 staining in mammary and extramammary Paget's disease.
Case reports have been published on the use of imiquimod in patients with extramammary Paget's disease.