extracellular matrix

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extracellular matrix

the aggregate of proteins secreted by cells.
Farlex Partner Medical Dictionary © Farlex 2012

extracellular matrix

Non-living material secreted by cells that fills spaces between the cells in a tissue, protecting them and helping to hold them together. The extracellular matrix may be semifluid or rigidly solid and hard as in bone. It is composed mainly of protein and includes collagens, elastin, reticulin, glycoproteins, proteoglycans, fibronectin, laminins and osteopontin.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

extracellular matrix (ECM)

see MATRIX.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
References in periodicals archive ?
The stromal 1 signature reflected extracellular-matrix deposition and histiocytic infiltration.
In addition to degrading numerous extracellular-matrix components, MMP3 can activate gelatinase B and the collagenases and release several cell surface molecules, including E-cadherin, a known contributor to cancer development (6).

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