exosome

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exosome

(ĕk′sō-sōm′)
n.
1. A tiny vesicle created and released from the plasma membrane of various types of cells, especially immune cells, and capable of inducing antigen-specific immune responses.
2. A cellular protein complex containing enzymes that degrade nuclear and cytoplasmic RNA.

exosome

(ĕks′ō-sōm″) [″ + Gr. soma, body]
An intracellular complex that degrades and processes messenger RNA molecules.

exosome

a protein complex containing NUCLEASES involved in degrading mRNA in eukaryotes.
References in periodicals archive ?
In our study, we extracted exosomes from the peripheral blood of the partially hepatectomized rats and identified the differential expression miRNAs through miRNAs microarray.
The new study builds upon a series of previously published studies in which NX Prenatal has demonstrated that the enrichment of exosome and microvesicle particles from maternal blood and subsequent proteomic analysis enables risk stratification of spontaneous preterm birth in the first trimester of pregnancy.
M2 EQUITYBITES-December 19, 2017-Evox Therapeutics partners with Boehringer Ingelheim for exosome drug delivery vehicles
Want to learn about exploiting exosomes for therapeutic use in patients with cystic fibrosis?
Scientists working on the technology hope to produce a portable scanner that can look for exosomes within a blood sample and provide rapid diagnosis.
The researchers extracted miRNA-containing exosomes from hypothalamic stem cells and injected them into the cerebrospinal fluid of two groups of mice: middle-aged mice whose hypothalamic stem cells had been destroyed and normal middle-aged mice.
They say exosomes act as "biological signalling systems", communicating between cells, carrying proteins, lipids, DNA and RNA.
Researchers at the National Eye Institute isolated exosomes from bone marrow stem cells and performed weekly injections of the stem cell secretions into the rats' vitreous.
Exosomes are tiny membrane-enclosed packages that form inside of cells before getting expelled.
However, none have interrogated micro RNA (miRNA) in exosomes of bladder cancer.
Reported recently, the IBM team's results show size-based separation of bioparticles down to 20 nanometers (nm) in diameter, a scale that gives access to important particles such as DNA, viruses and exosomes.
Our expertise is therefore in the isolation and downstream analysis of the exosomes and their contents.