exonucleases


Also found in: Dictionary, Thesaurus, Encyclopedia.

exonucleases

Enzymes that break down DNA and RNA molecules, starting at the ends of the molecular chains. Exonucleases split off nucleotides one at a time from the end of a chain and may be specific for either end.
References in periodicals archive ?
The 3' phosphorylated primers were used for the digestion of dsDNA by lambda exonuclease in order to get ssDNA.
Redundant exonuclease involvement in Escherichia coli methyl-directed mismatch repair.
Cellectis's teams thus succeeded in improving current genome engineering techniques by employing a new approach: co-expressing meganucleases or TALENs[TM], Cellectis's internal technology, together with exonucleases.
However, if the DNA polymerase used has an associated 5'-3' exonuclease activity (e.