excitatory postsynaptic potential

(redirected from Excitatory postsynaptic potentials)

ex·cit·a·to·ry post·syn·ap·tic po·ten·tial (EPSP),

the change in potential that is produced in the membrane of the next neuron when an impulse that has an excitatory influence arrives at the synapse; it is a local change in the direction of depolarization; summation of these potentials can lead to discharge of an impulse by the neuron.

ex·cit·a·to·ry post·syn·ap·tic po·ten·tial

(ek-sī'tă-tōr-ē pōst'si-nap'tik pŏ-ten'shăl)
The change in potential that is produced in the membrane of the next neuron when an impulse that has an excitatory influence arrives at the synapse; it is a local change in the direction of depolarization; summation of these potentials can lead to discharge of an impulse by the neuron.

excitatory postsynaptic potential (EPSP)

a reduction in the RESTING POTENTIAL of a postsynaptic cell caused by the arrival of TRANSMITTER SUBSTANCE from the presynaptic cell. The reduction takes the membrane potential close to the THRESHOLD and, therefore, nearer to itself forming an ACTION POTENTIAL. see FACILITATION.
References in periodicals archive ?
CBI-3 also produces rapid excitatory postsynaptic potentials (EPSPs) in B40, resulting in feedforward inhibition of egestive motor patterns.
with [E.sub.i] = [E.sub.i](t), t [greater than or equal to] 0 and [I.sub.j] = [I.sub.j](t), t [greater than or equal to] 0 as Poisson processes with rates [[lambda].sub.E,i](t) and [[lambda].sub.I,j](t), a > 0 and b > 0 being the magnitude of each excitatory postsynaptic potential (EPSP) and inhibitory postsynaptic potential (IPSP); a cell receives excitatory postsynaptic potentials (EPSPs) at p synapses and inhibitory postsynaptic potentials (IPSPs) at q inhibitory synapses.
Field excitatory postsynaptic potentials (fEPSPs) induced by lateral and medial perforant path stimulation in acute slices also differ in their kinetics, suggesting differences in the vesicle release probabilities of these synapses [54, 55].
Methods: Field excitatory postsynaptic potentials (fEPSPs), spontaneous excitatory postsynaptic currents (sEPSCs) and miniature spontaneous excitatory postsynaptic currents (mEPSCs) were recorded, by using in vitro field potential electrophysiology and whole-cell patch clamp techniques in acute hippocampal slices from rats.
But once these synapses are mature, they strongly inhibit the excitatory postsynaptic potentials (EPSP) [5].
Therefore, in the present study we tested whether TDE can modulate dendritic field excitatory postsynaptic potentials (fEPSPs), which indicate the neuronal synaptic function, in Cornu Ammonis 1 (CA1) hippocampal slices of normal rats as found in current AChE-I drugs used for AD therapy.
This increase in L-type channels is correlated with increased failure of excitatory postsynaptic potentials as well as increased susceptibility to cell death.
Extracellular field excitatory postsynaptic potentials (fEPSPs) recorded in the stratum radiatum were evoked with a bipolar stimulus electrode positioned in the stratum molecularae/luminaris to evoke glutamate release from Schaffer collaterals (0.05 Hz).
Calcium dynamics in single spines during coincident pre- and postsynaptic activity depend on relative timing of back-propagating action potentials and subthreshold excitatory postsynaptic potentials. Proc.
Halogenated aromatic hydrocarbons suppress CA1 field excitatory postsynaptic potentials in rat hippocampal slices.
A single 100 Hz tetanus (1 s) is applied (stim), to induce LTP (recordings of field excitatory postsynaptic potentials; fEPSP) in slices prepared from either pilocarpine- or vehicle-injected animals (stratum radiatum, rad; stratum lacunosummoleculare, la.-mol.; stratum moleculare, mL; dentate gyrus, DG; nuclear stain, TO-PRO; scale bar: 200 [micro]m).
These APs propagate to synapses and elicit excitatory postsynaptic potentials (EPSPs).