Ewing's sarcoma

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 [sahr-ko´mah] (pl. sarcomas, sarco´mata.)
A tumor, often highly malignant, composed of cells derived from connective tissue such as bone, cartilage, muscle, blood vessel, or lymphoid tissue; sarcomas usually develop rapidly and metastasize through the lymph channels. Different types are named for the specific tissue they affect: fibrosarcoma in fibrous connective tissue; lymphosarcoma in lymphoid tissues; osteosarcoma in bone; chondrosarcoma in cartilage; rhabdosarcoma in muscle; and liposarcoma in fat cells. adj., adj sarco´matous.
Abernethy's sarcoma a malignant fatty tumor occurring mainly on the trunk.
alveolar soft part sarcoma one with a reticulated fibrous stroma enclosing groups of sarcoma cells enclosed in alveoli walled with connective tissue.
botryoid sarcoma (sarcoma botryoi´des) an embryonal rhabdomyosarcoma arising in submucosal tissue, usually in the upper vagina, cervix uteri, or bladder neck in young children and infants, presenting grossly as a polypoid grapelike structure.
endometrial stromal sarcoma a pale, polypoid, fleshy, malignant tumor of the endometrial stroma.
Ewing's sarcoma a malignant tumor of the bone that arises in medullary tissue, usually found in cylindrical bones, with pain, fever, and leukocytosis as prominent symptoms; called also Ewing's tumor.
giant cell sarcoma a malignant form of giant cell tumor of bone.
granulocytic sarcoma chloroma.
immunoblastic sarcoma of B cells an aggressive B-cell lymphoma believed to arise from transformed interfollicular B lymphocytes, which in many cases is associated with a preexisting immunologic disorder, e.g., Sjögren's syndrome, systemic lupus erythematosus, or Hashimoto's thyroiditis, or with an immunocompromised state.
immunoblastic sarcoma of T cells a group of T-cell lymphomas comprising tumors derived from T lymphocytes in the paracortical area arising from a mixture of small lymphocytes and many large transformed cells; the latter are characterized by one or more small but distinctly eosinophilic nucleoli.
Kaposi sarcoma a multicentric, malignant neoplastic vascular proliferation characterized by bluish red cutaneous nodules, usually on the lower extremities, most often on the toes or feet; the nodules slowly increase in size and number and spread to more proximal sites. Tumors often remain confined to skin and subcutaneous tissue, but widespread visceral involvement may occur. The condition occurs endemically in certain parts of Central Africa and Central and Eastern Europe, and a particularly virulent and disseminated form occurs in immunocompromised patients such as transplant recipients and those with acquired immunodeficiency syndrome. Human herpesvirus 8 has been implicated as a causative agent.
lymphatic sarcoma diffuse lymphoma.
osteogenic sarcoma a malignant primary tumor of bone composed of a malignant connective tissue stroma with evidence of osteoid, bone, and/or cartilage formation; depending upon the dominant component, classified as osteoblastic, fibroblastic, or chondroblastic.
pseudo–Kaposi sarcoma unilateral subacute to chronic dermatitis, often with postinflammatory hyperpigmentation, occurring in association with underlying arteriovenous fistula, which closely resembles Kaposi sarcoma both clinically and histologically.
reticulum cell sarcoma histiocytic lymphoma.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
References in periodicals archive ?
Ewing's sarcoma is the second most common bone tumor; it usually manifests during the first 2 decades of life.
Genetic analysis showed an 11-22 translocation (Ewing's Sarcoma breakpoint region one) gene rearrangement.
The histopathology report revealed that the patient had a round cell tumor, which was positive for Ewing's sarcoma, EWS-FLI1 fusion gene, and membranous expression of CD99 and S-100 proteins.
CONCLUSION: Extraosseouss Ewing's Sarcoma is a rare tumor.
According to the American Joint Committee on Cancer (AJCC) classification system, the patient was staged as a G3T2N0M1, Stage IV Ewing's sarcoma.
Whatever the reason, Ewing's relationship with Lion was short-lived.
Differentiating lymphoblastic lymphoma from Ewing's sarcoma: lymphocyte markers and gene rearrangement.
Dixon told his support worker, Miss Ewing's colleague Mark Ellis, that he'd gone to London after he'd got bored and gone on a drinking bender.
Ewing's sarcoma tends to be poorly differentiated, whereas PNET most often shows definite neuroectodermal differentiation.
In Ewing's eyes, this commitment far exceeded the policyholders' expected customer service.
Also very highly recommended reading from Pixy Jack Press is Rex Ewing's "Got Sun?
The self-styled Queen City of the West had also become an early center of the meatpacking industry, "the nation's premier hog-slaughterer and supplier of cured hams." (1) In Bob Ewing's day, Cincinnati was still nicknamed Porkville or Porkopolis, and the ball club was called the Porkers or Porkopolitans.