Evans syndrome


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Ev·ans syn·drome

(ev'ănz),
acquired hemolytic anemia and thrombocytopenia.

Ev·ans syn·drome

(ev'ănz sin'drōm)
Acquired hemolytic anemia and thrombocytopenia.

Evans,

Robert S., U.S. physician, 1912-1974.
Evans syndrome - acquired hemolytic anemia and thrombocytopenia.

Ev·ans syn·drome

(ev'ănz sin'drōm)
Acquired hemolytic anemia and thrombocytopenia.
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References in periodicals archive ?
She was diagnosed with eclampsia associated with Evans syndrome. Foetal cardiac ac tivity was normal but termination of the pregnancy was planned considering the mother's health.
Two patients presenting with autoimmune thrombocytopenia and anemia were diagnosed with Evans syndrome by the pediatric hematology department.
It has been associated with hematologic diseases, malignancies, renal angiomyolipomas or infarction, and Evans syndrome [1-3], while it has been shown to be more common in patients receiving systemic anticoagulation, as shown in 2 recent studies [4, 5].
Evans syndrome (ES) is a rare autoimmune disorder first described in 1951 whose exact pathophysiology is unknown [1, 2].
A rare case of superior sagittal sinus thrombosis has been reported in association with Evans syndrome of hemolytic anemia, [7] but as far as we know the association of cerebral vein thrombosis with TTP is extremely rare.
One 11-year-old boy with chronic disease was finally diagnosed as Evans syndrome, with positive direct antiglobulin test and markers of hemolysis, two years after diagnosis.
About 5-10% of patients have both thrombocytopenia and AIHA, otherwise known as Evans syndrome [9,10].
In the differential diagnostic workup of APS-related thrombocytopenia one should always exclude, in addition to SLE, pseudothrombocytopenia, TTP, DIC, and HIT and, when hemolytic anemia is present, Evans syndrome, a hematological condition reported to be associated with APS [49].
Therefore, Evans syndrome (ES) should be presented separetly then autoimmune hemolytic anemia (AIHA) as of Wiskott-Aldrich syndrome (WAS) in which Coombs positivity may develop as of alloimmune reaction.
Rituximab has been used to treat idiopathic thrombocytopenic purpura (ITP) and Evans syndrome, described in several case reports and in small trials, with positive results.
After six weeks in the Arrowe Park Hospital on Merseyside, doctors confirmed that he had a rare blood disorder called Evans Syndrome. There is no known cure, the medical community have yet to discover a specific cause - and it can be fatal.