Evans blue


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Evans blue

 [ev´anz]
an odorless green, bluish green, or brown powder dye, used as a diagnostic acid in estimation of blood volume. The dye is injected into the bloodstream and after a sufficient period of time samples of the blood are taken to determine the degree of dilution of the dye.

Ev·ans blue

(ev'ănz), [C.I. 23860]
A diazo dye used for the determination of the blood volume on the basis of the dilution of a standard solution of the dye in the plasma after its intravenous injection; it binds to proteins and is also used as a vital stain for following diffusion through blood vessel walls.
Synonym(s): azovan blue

Ev·ans blue

(ev'ănz blū)
[CI 23860] A diazo dye used for the determination of the blood volume on the basis of the dilution of a standard solution of the dye in the plasma after its intravenous injection; binds to proteins; used as a vital stain for following diffusion through blood vessel walls.

Evans,

H.M., U.S. anatomist and physiologist, 1882-1971.
Evans blue - a diazo dye used as a vital stain for following diffusion through blood vessel walls. Synonym(s): azovan blue
References in periodicals archive ?
Among those, Evans blue (EB) dye is just one that has a long history as a biological dye and clinical diagnostic agent [5].
Compared with the brains of the sham-treated mice, the extravasated content of Evans blue was substantially higher in both hemispheres of the mouse model of SAH, and XMU-MP-1 (15 mg/kg) significantly alleviated the leakage (Figure 5(a)).
In brief, rats were given the caudal venous injection of 5% Evans blue (EB) (Sigma Aldrich, Germany) at the dose of 1 ml/kg.
Vascular permeability assays in vivo using Evans blue dye can be useful in overcoming the limitation of cellular and membrane-based experiments.
It has been well established that the intraperitoneal injection of acetic acid greatly enhances vascular permeability and facilitates the vascular leakage of Evans blue dye [13].
Bastille, "Tissue-specific extravasation of albumin-bound Evans blue in hypothermic and rewarmed rats," Canadian Journal of Physiology and Pharmacology, vol.
To verify the effectiveness and validity of ICV injection of H89 in rats in the Acu + H89 and FLX + H89 groups, another 6 rats were subjected to ICV catheterization and ICV injection of 1% Evans blue. Briefly, rats that received posttraining infusions of 0.9% sodium chloride solution after successful ICV catheterization were returned to the holding cage for better recovery for 7 days from surgery.
A separate group of animals subjected to the same experimental procedures were killed by pentobarbital overdose, and fresh spinal tissues were collected for edema and Evans blue extravasation quantifications.
N-Nitro-L-arginine methyl ester hydrochloride (L-NAME), D-galactose, bovine serum albumin (BSA), Coomassie brilliant blue, G-250, formamide and Evans blue were obtained from Sigma Chemical-Aldrich (St.