etretinate


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etretinate

Pharmacology A retinoic acid derivative that stimulates epithelial differentiation and inhibits the malignant transformation of skin and mucosa; it is a 2nd line agent for psoriasis in combination with PUVA, to ↓ dose of methoxsalen. See Psoriasis.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

etretinate

(ĕ-trĕt′ĭn-āt)
A tretinoin drug formerly used to treat severe recalcitrant psoriasis.

CAUTION!

Etretinate must not be used by women who are pregnant or who intend to become pregnant. It should be prescribed only by physicians knowledgeable in the systemic use of retinoids.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
This study examined efficacy and safety in Japanese patients diagnosed with generalized pustular psoriasis (GPP) who have had an inadequate response to conventional therapy (e.g., etretinate and cyclosporine).
Bukhari, "Impetigo herpetiformis in a primigravida: successful treatment with etretinate," Journal of drugs in dermatology : JDD, vol.
The second-generation retinoids are the monoaromatics (etretinate, acitretin, and motretinate).
Furukawa, "The vitamin A derivative etretinate improves skin sclerosis in patients with systemic sclerosis," Journal of Dermatological Science, vol.
Etretinate 1 mg/kg/day is helpful in some cases, but the lesions recur.
In some cases of treatment-resistant and unresectable cancers, etretinate has provided partial improvement [1, 6].
A Japanese study combined the use of low-dose etretinate (0.3-0.5 mg/kg per day) and EPA and compared it with the high-dose etretinate.
Acitretin, a synthetic retinoid, is the pharmacologically active metabolite of etretinate. Acitretin is currently approved by the US Food and Drug Administration for the treatment of severe psoriasis in adults.
Sensory neuropathy associated long-terme etretinate (ET) therapy.
The skin lesions healed after several treatments with different drugs, including etretinate and chloroquine, but visible scars developed in the areas where the lesions have been present.
You cannot donate blood if you have ever taken etretinate (Tegison) or human pituitary-derived growth hormone.