5 [micro]g/mL), cycloserine (70 [micro]g/mL), ethionamide
inhA, a gene encoding a target for isoniazid and ethionamide
in Mycobacterium tuberculosis.
In both these cases, Ethionamide
was replaced by PAS.
activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis.
Ortiz de Montellano, The Antituberculosis Drug Ethionamide
is Activated by a Flavoprotein Monooxygenase, J.
Treatment for TB includes a combination of anti-tubercular medications including isoniazid, rifampin, pyrazinamide, ethambutol, streptomycin, ethionamide
and cycloserine, administered over a span of 12 to 13 months.
So, the second-line ATD (kanamycin, ethionamide
, levofloxacin, ethambutol, pyrazinamide, and cycloserine) was started.
STR or kanamycin, EMB, MOX, ethionamide
either amikacin or kanamycin), any first-line drug to which the isolate is susceptible (Table 1), and the addition of category 3 drugs such as cycloserine/terizidone, ethionamide
, and others, such that at least 4 drugs, to which the isolate is likely to be susceptible, are being used
a) Kanamycin, Levofloxacin, Ethionamide
, Pyrazinamide, Ethambutol, Cycloserine
TABLE 1 Drugs that are potential acne triggers Common drugs/drug classes Anabolic steroids (eg, danazol and testosterone) Bromides and iodides Corticosteroids (eg, prednisone) Corticotropin Isoniazid and ethionamide
Lithium and barbiturates Phenytoin and trimethadione Less common drugs Azathioprine Cyclosporine Disulfiram Phenobarbital Quinidine Adapted from: Sterry W, et el.
Since 2005, CDC has received reports of difficulty obtaining each of the following SLDs: streptomycin, cycloserine, ethionamide
, rifabutin, amikacin, capreomycin, and kanamycin.