Bullous impetigo is the result of a staphylococcal infection, which produces an epidermolytic
toxin leading to bulla formation.
When the researchers examined patients from the registry who have epidermolytic
presentations, 100% had mutations in the known genes, "so the biopsy is diagnostic," Dr.
Linear psoriasis and systematized epidermolytic
The coagulase-positive Staphylococcus aureus produces two epidermolytic
or exfoliative toxins (ETs), ETA and ETB, which induce this clinical condition.
Similar lesions have been described in one case of hereditary epidermolytic
palmoplantar keratoderma (vorner type).
Epidermal acanthosis and hyperkeratosis are histopathological characteristics that are commonly observed in chloracne (Panteleyev and Bickers 2006) and epidermolytic
hyperkeratosis, a genetic disorder associated with keratin mutations (Muller et al.
Severe Cutaneous Adverse Reactions: Emergency Approach to NonBurn Epidermolytic
Disorders Defect Inheritance Defect in [alpha]-helical rod pattern Epidermolysis K5/K14 Autosomal bullosa simplex dominant Epidermolytic
K1/K10 Autosomal ichthyosis dominant Pachyonychia K6/16, K17 Autosomal congenita dominant Epidermolytic
K9 Autosomal palmoplantar dominant keratoderma Defects outside [alpha]- helical rod domain Non-epidermolytic
N-terminal of Autosomal palmoplantar K1, in a region dominant keratoderma that is known to bind to desmoplakin Epidermolysis Non-helical bullosa with head domain of mottled K5 pigmentation Disorders of keratin associated proteins Ichthyosis Mutation in the gene Autosomal vulgaris encoding filaggrin dominant (FLG).
Muller FB, Huber M, Kinaciyan T, et al: A human keratin 10 knockout causes recessive epidermolytic
GOTHENBURG, SWEDEN--Botulinum toxin injections to the soles of the feet are a highly effective, safe, and long-lasting treatment for painful blistering and calluses in patients with sweat-exacerbated epidermolytic
keratopathies, according to Dr.
palmoplantar keratoderma of Varner: re-evaluation of Varner's original family and identification of a novel keratin 9 mutation.
hyperkeratosis and focal acantholytic dyskeratosis in common acquired melanocytic nevi and atypical melanocytic lesions.