Pfizer originally manufactured and sold the capsules to UK wholesalers and pharmacies as Epanutin
Seizures were controlled with phenytoin (Epanutin
; Pfizer, NY, USA) at a loading dose of 20 mg/kg, and phenytoin was administered at 300 mg/day as an add-on therapy.
Acceleration of gingival wound healing in non-epileptic patients receiving diphenylhydantoin sodium (Dilantin, Epanutin
The regulatory agency alleges that the two companies removed the official brand name, Epanutin, from Pfizer's phenytoin sodium capsule product in 2012, rendering it a generic so they could increase the price by as much as 2,600% to the U.K.'s National Health Service (NHS).
Pfizer responded that Epanutin was a loss-making product and the arrangement with Flynn Pharma allowed the drug to remain available to patients in the U.K.
The Competition and Markets Authority said that in 2012 Pfizer sold the UK distribution rights of Epanutin
to Flynn, based in Stevenage, Herts, which marketed its own version.
A dozen pharmacies were contacted by The Daily Star to inquire about the availability of Epanutin, a drug used by patients with epilepsy to prevent seizures and whose active ingredient is called Phenytoin.
But Yamout said patients had been calling him for the last 10 days complaining of the unavailability of Epanutin. He said he was unsure of the reason for the shortage, though some pharmacies say an alternative drug may be available in the coming days.
Avoid phenytoin (Epanutin
) because it shares pharmacological properties with lignocaine and may potentiate toxicity.
Furthermore, a mental hospital in Lebanon is experiencing a major crisis, as its supply of Epanutin
, an anti-convulsion drug used to treat schizophrenic patients is days from running out.
I'm taking epanutin
for epilepsy but I'm told it doesn't mix with modern drugs.
The British Court of Appeal has upheld Flynn Pharma's right to stop the parallel importation of Pfizer's (NYSE: PFE) Epanutin
(phenytoin sodium) anti-epileptic drug into the UK for resale as Phenytoin Sodium Flynn, the company announced on Thursday.