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A leukocyte with coarse, round granules present.
Mentioned in: Histiocytosis X

eosinophils (ēˑ·ō·si·n·filzˈ),

n.pl white blood cells of the granulocyte type that have rough, round granules of cytoplasm that stain with eosin.
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He also observed that the reduced white blood cell and eosinophil counts were consistent with the dramatic reduction in lung lesions that the Company has recently reported.
In both the high eosinophils patient group and overall patient group : Dupilumab showed a reduction in adjusted annualized rate of severe exacerbations compared to placebo (64 to 75 percent reduction, p less than 0.
A finding of more than 5 eosinophils in 3 to 5 fields of view or a single finding of 20 to 30 cells (score: [greater than or equal to] 1) (11) was considered to represent a positive finding for nasal eosinophilia.
Clinical trials have shown that reslizumab significantly reduced the rate of asthma exacerbations and improved lung function in a specific group of patients with elevated eosinophil levels.
2) IFN-[gamma] inhibits allergic responses via its capacity to inhibit the effect of IL-4 on B cells and eosinophils.
Organizations, healthcare providers, and institutions around the globe are joining APFED to recognize National Eosinophil Awareness Week by sharing information with their communities and with the public.
The persistence of eosinophilia for an extended period of time can cause damage to various body tissues, mainly due to release of the contents of cytoplasmic granules in eosinophils (4).
On the other hand, elevated B-lymphocytes have been shown to correlate more to mast cell presence than eosinophils (Vicario 2010, Mulder 2011).
A Eosinophils are produced by the bone marrow, circulate in the peripheral blood for a short time, and eventually localize in various tissues and organs such as the skin, lungs, and G1 tract.
A near-complete response was 10 or fewer eosinophils per high-powered field (70% of patients), and a partial response was a 50% or greater reduction in peak eosinophil count (78% of patients).
Only 53% of these patients had eosinophils in their mucus samples; 47% did not.