eosinophilic esophagitis


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Related to eosinophilic esophagitis: Eosinophilic gastroenteritis

eosinophilic oesophagitis

A benign, possibly allergic condition, which affects young males with dysphagia.
 
Clinical findings
Symptoms of gastrooesophageal reflux disease—e.g., epigastric and chest pain, heartburn, nausea, vomiting, regurgitation, dysphagia with motility disturbances; often associated with extra-intestinal allergic symptoms (e.g., asthma, chronic rhinitis, eczema). May present late with strictures.

Endoscopy
White punctate lesions, white exudate, ringed appearance, linear furrows.

DiffDx
Reflux oesophagitis, oesophageal leiomyomatosis, eosinophilic gastroenteritis.

Management
Corticosteroids, dietary restriction.

eosinophilic esophagitis

Dysphagia and heartburn resulting from allergy to inhaled or consumed antigens. Biopsies of the esophagus reveals infiltration of the mucosa by eosinophils. It is treated with corticosteroids.
See also: esophagitis
References in periodicals archive ?
Esophageal rupture as a primary manifestation in eosinophilic esophagitis. Case Rep Med 2014; 2014:673189.
Eosinophilic esophagitis in children and adults: a systematic review and consensus recommendations for diagnosis and treatment.
The FLUTE study is part of Adare Pharmaceuticals HARMONY Clinical Trial programme, which is focused on the development of APT-1011 in eosinophilic esophagitis in adults, adolescents and children.
Berman, "Eosinophilic esophagitis in children and adolescents with abdominal pain: comparison with eoedysphagia and functional abdominal pain," Canadian Journal of Gastroenterology and Hepatology, vol.
Arias et al., "Guidelines on eosinophilic esophagitis: evidence-based statements and recommendations for diagnosis and management in children and adults," United European Gastroenterology Journal, vol.
Ruchelli, "Primary eosinophilic esophagitis in children: successful treatment with oral corticosteroids," Journal of Pediatric Gastroenterology and Nutrition, vol.
Atopic dermatitis, contact dermatitis, eosinophilic gastropathy and eosinophilic esophagitis may develop due to mixed type food allergies (1).
Eosinophilic esophagitis in a patient with vigorous achalasia.
Shire said the transaction gives it the acquisition of global rights to-and undertaken the further development of Meritage's Phase 3-ready compound, Oral Budesonide Suspension (OBS), for the treatment of adolescents and adults with eosinophilic esophagitis, a rare, chronic inflammatory gastrointestinal (GI) disease.
With the acquisition, Shire has acquired the global rights to-and undertaken the further development of-Meritage's Phase 3-ready compound, Oral Budesonide Suspension, for the treatment of adolescents and adults with eosinophilic esophagitis, a rare, chronic inflammatory gastrointestinal disease.
[11.] Papadopoulou A, Koletzko S, Heuschkel R, et al., ESPGHAN Eosinophilic Esophagitis Working Group and the Gastroenterology Committee.
Topical steroid therapy improved some indicators of mucosal integrity in patients with eosinophilic esophagitis, but proton pump inhibitor therapy did not, two studies showed.

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