enterochromaffin cell

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Related to Enterochromaffin cells: serotonin, carcinoid syndrome

enterochromaffin cell

Abbreviation: EC cell
An enteroendocrine cell that produces serotonin and is found in the small intestine. Enterochromaffin cells are very similar to the cells, found throughout the peripheral sympathetic nervous system, that are called simply 'chromaffin cells'.
See also: cell
References in periodicals archive ?
Enterochromaffin cells release melatonin into nearby blood vessels of the mucous membrane of the inner lining of the stomach and intestines.
Pulmonary arterial hypertension has been described in type Ia, possibly due to an abnormally excessive production of vasoconstrictor amines like serotonin that is synthesized from the intestinal enterochromaffin cells. Hence, this becomes a plausible means in studying patients suspected of having type Ia glycogenosis; however, we should not discard the effect caused by the endothelial damage from the presence of metabolic alterations like hyperlipemia (3,4).
In mammals, the enterochromaffin cells synthesize 90% of the 5-HT in the enteric nervous system and release 5-HT hormonally in response to mechanical or chemical stimulation (Erspamer.
It is secreted by the enterochromaffin cells of the microvilli and it promotes peristalsis in the GIT.
In midgut carcinoids derived from enterochromaffin cells located in the small intestines, cecal region, and ascending colon (10), serotonin (5-hydroxytryptamine) is the major metabolic product.
Moreover, it has been reported that the expression of T lymphocytes, enterochromaffin cells, and interleukin-1[beta] was increased in the lamina propria of the colons of patients with IBS (5-7).