enterochromaffin cell

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Related to Enterochromaffin cells: serotonin, carcinoid syndrome

enterochromaffin cell

enterochromaffin cell

Abbreviation: EC cell
An enteroendocrine cell that produces serotonin and is found in the small intestine. Enterochromaffin cells are very similar to the cells, found throughout the peripheral sympathetic nervous system, that are called simply 'chromaffin cells'.
See also: cell
References in periodicals archive ?
Pulmonary arterial hypertension has been described in type Ia, possibly due to an abnormally excessive production of vasoconstrictor amines like serotonin that is synthesized from the intestinal enterochromaffin cells.
In mammals, mechanical and chemical stimuli lead to release of 5-HT from the enterochromaffin cells, which are paraneurons located in the gastrointestinal mucosa that produce nearly all of the intestinal 5-HT (Erspamer, 1966).
It is secreted by the enterochromaffin cells of the microvilli and it promotes peristalsis in the GIT.
In midgut carcinoids derived from enterochromaffin cells located in the small intestines, cecal region, and ascending colon (10), serotonin (5-hydroxytryptamine) is the major metabolic product.